True North

True North is the direction along a meridian toward Earth’s geographic North Pole, providing a fixed reference for orientation and measurement. In engineering, it is established from geographic coordinates, astronomical observations, or geodetic models, unlike Magnetic North, which varies with location and changes over time because of Earth’s magnetic field. Engineers use True North to define azimuths and bearings, align surveys and maps, orient infrastructure, and coordinate navigation or site plans. Distinguishing it from magnetic direction helps maintain consistent spatial references, reduce alignment errors, and support accurate communication across surveying, civil, geospatial, and transportation projects.

True North - Related Videos

Education

JoVE Core - Mechanical Engineering

True Stress and True Strain

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2024

Engineering stress is calculated as the load divided by the original, undeformed cross-sectional area. It approximates a material under load. This approximation is especially relevant post-yield in ductile materials. Though engineering stress-strain diagrams are often used for their convenience and accessibility, they can sometimes fall short in accuracy, particularly when dealing with large strain values. In contrast, true stress offers a more precise portrayal. It is computed by dividing the...

Research

JoVE Journal - Immunology and Infection

Detection of True IgE-expressing Mouse B Lineage Cells

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Cited by 3 •

2014

In vitro analysis of class switch recombination in mice is challenging due to cytophilic IgE molecules bound to Fc receptors on the surface of B cells. We describe a method for IgE detection using trypsin-mediated cleavage of surface-bound IgE prior to fixation and permeabilization for cytoplasmic fluorescence staining.

TRUE Gene Silencing: Screening of a Heptamer-type Small Guide RNA Library for Potential Cancer Therapeutic Agents

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Cited by 7 •

2016

Here we present a protocol for screening of a heptamer-type sgRNA library for potential therapeutic drugs against blood cancers.

A General Method for Evaluating Incubation of Sucrose Craving in Rats

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Cited by 25 •

2011

Responding for food or drug-paired cues increases over the course of a period of abstinence and this may relate to an increased susceptibility to relapse behaviors. Here we detail a procedure for evaluating this "incubation of craving" in rats that have self-administered sucrose.

Using Coculture to Detect Chemically Mediated Interspecies Interactions

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Cited by 9 •

2013

Bacteria produce secreted compounds that have the potential to affect the physiology of their microbial neighbors. Here we describe a coculture screen that allows detection of such chemically mediated interspecies interactions by mixing soil microbes with fluorescent transcriptional reporter strains of Bacillus subtilis on solid media.

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