Ultra Sensitive Scale
Ultra Sensitive Scale - Related Videos
14:18
A Strategy for Sensitive, Large Scale Quantitative Metabolomics
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Cited by 28 •
2014
Metabolite profiling has been a valuable asset in the study of metabolism in health and disease. Utilizing normal-phased liquid chromatography coupled to high-resolution mass spectrometry with polarity switching and a rapid duty cycle, we describe a protocol to analyze the polar metabolic composition of biological material with high sensitivity, accuracy, and resolution.
07:34
Large Scale Non-targeted Metabolomic Profiling of Serum by Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-MS)
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Cited by 18 •
2013
Non-targeted metabolite profiling by ultra performance liquid chromatography coupled with mass spectrometry (UPLC-MS) is a powerful technique to investigate metabolism. This article outlines a typical workflow utilized for non-targeted metabolite profiling of serum including sample organization and preparation, data acquisition, data analysis, quality control, and metabolite identification.
02:41
pH Scale
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2020
Hydronium and hydroxide ions are present both in pure water and in all aqueous solutions, and their concentrations are inversely proportional as determined by the ion product of water (Kw). The concentrations of these ions in a solution are often critical determinants of the solution’s properties and the chemical behaviors of its other solutes. Two different solutions can differ in their hydronium or hydroxide ion concentrations by a million, billion, or even trillion times. A common means of...
05:28
MALDI Sample Preparation: the Ultra Thin Layer Method
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Cited by 32 •
2007
This video demonstrates the preparation of an ultra-thin matrix/analyte layer for analyzing peptides and proteins by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS).
08:53
Angle-resolved Photoemission Spectroscopy At Ultra-low Temperatures
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Cited by 8 •
2012
The overall goal of this method is to determine the low-energy electronic structure of solids at ultra-low temperatures using Angle-Resolved Photoemission Spectroscopy with synchrotron radiation.
FAQs
The instrument detects the force produced by the sample and converts that signal into a mass value through calibration. This process allows the scale to represent extremely small masses or mass differences numerically rather than relying on visual estimation. In laboratory work, the calibrated output supports more consistent reagent preparation and improves the reproducibility of measurements.
These environmental factors can interfere with the force signal or make the measured value less stable. Controlling them helps the instrument distinguish the sample’s contribution from unwanted physical effects. Stable weighing conditions therefore reduce variation between measurements, which is especially important when small amounts of reagents or nucleic-acid standards influence later concentration calculations.
Calibration establishes how the detected force corresponds to the displayed mass, allowing the instrument to report small differences in a consistent way. Without a reliable calibrated relationship, a reading may not accurately represent the material being measured. In genetics workflows, dependable calibration strengthens comparisons among prepared samples, standards, and repeated experiments.
It can support the weighing of reagents, nucleic-acid standards, and other materials used in genetic analysis. These materials may contribute to workflows involving DNA extraction, amplification, sequencing, or molecular analysis. Accurate mass measurements help laboratories prepare inputs more consistently, supporting concentration calculations and reducing variation that could otherwise affect comparisons across experiments.
The measured mass contributes to determining how much material is present when a preparation is made, so greater precision can improve the resulting concentration calculation. More reliable concentrations help limit variation among samples and standards. This matters when genetic workflows compare molecular measurements, because differences in starting material can reduce the comparability of results.
Its precision is useful when preparing materials for DNA extraction, amplification, sequencing, and broader molecular analysis. The scale does not replace those genetic methods; instead, it supports their preparation and measurement steps by providing reliable mass information. Better-controlled inputs can improve reproducibility and make results from separate genetic experiments easier to compare.