Cardiac Defibrillation
Cardiac Defibrillation - Related Videos
08:33
Porcine Cardiac Arrest Model Using an Implantable Defibrillator
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2026
This protocol demonstrates the use of an implantable cardioverter-defibrillator (ICD) to reliably induce ventricular arrhythmias, perform internal cardioversion, and obtain intracardiac ECG recordings in a porcine model.
16:40
A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
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Cited by 5 •
2012
Dual-chamber implantable cardioverter-defibrillators (ICDs) may improve detection of atrial fibrillation as well as differentiation of tachycardias. However, this advantage is undermined by complications associated with the second electrode, which is required in conventional dual chamber devices. Therefore, BIOTRONIK has developed a new electrode called the LinoxSMART S DX that, when used in conjunction with the Lumax DX ICD, offers dual-chamber detection without the risks associated with the...
06:37
Pluripotent Stem Cell Derived Cardiac Cells for Myocardial Repair
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Cited by 13 •
2017
We present three novel and more efficient protocols for differentiating human induced pluripotent stem cells into cardiomyocytes, endothelial cells, and smooth muscle cells and a delivery method that improves the engraftment of transplanted cells by combining cell injection with patch-mediated cytokine delivery.
10:03
Basic Life Support: Cardiopulmonary Resuscitation and Defibrillation
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2015
Source: Julianna Jung, MD, FACEP, Associate Professor of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA High-quality cardiopulmonary resuscitation (CPR) is the single most important determinant of intact survival in cardiac arrest, and it is critical that all healthcare workers are able to perform this lifesaving technique effectively. Despite the conceptual simplicity of CPR, the reality is that many providers perform it incorrectly, resulting in suboptimal...
08:25
Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
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Cited by 11 •
2015
Streptococcus pneumoniae forms discrete non-purulent microscopic lesions in the heart. Outlined is the protocol for a murine model of cardiac microlesion formation. Instruction is provided on microlesion visualization using microscopy, discrimination between early and late microlesions, and methods to detect cardiac remodeling in hearts of convalescent animals.
FAQs
Simultaneous depolarization of a critical mass of cardiac muscle interrupts the widespread, chaotic electrical activity associated with ventricular fibrillation and pulseless ventricular tachycardia. This interruption creates an opportunity for the heart’s normal pacemaker systems to reestablish coordinated electrical activation and contraction, rather than allowing disorganized activity to continue.
The shock does not directly create a sustained normal heartbeat. Instead, it stops the abnormal electrical pattern across enough cardiac tissue for the heart’s intrinsic pacemaker systems to resume control. When those systems reestablish coordinated activity, the heart may recover an organized rhythm capable of supporting circulation.
Cardiac defibrillation is intended for ventricular fibrillation and pulseless ventricular tachycardia, the life-threatening rhythms identified in the source material. Its purpose is to terminate these abnormal ventricular rhythms and permit organized cardiac activity to return. The intervention therefore depends on recognizing whether the cardiac rhythm is one for which a shock is appropriate.
Both device types can deliver an electrical shock, but they differ in how rhythm decisions are handled. A manual defibrillator is operated by a trained user, whereas an automated external defibrillator analyzes the rhythm and advises or delivers a shock when appropriate. This analysis supports selection of shock treatment during emergency cardiac arrest care.
Cardiopulmonary resuscitation accompanies defibrillation during emergency treatment of sudden cardiac arrest. The source emphasizes that rapid defibrillation alongside CPR can improve the likelihood of restoring circulation. These interventions therefore function together in the emergency response: CPR is provided while the rhythm is assessed and shock treatment is used when appropriate.
Timing matters because defibrillation must interrupt the life-threatening ventricular rhythm before the opportunity to restore organized activity is lost. The source identifies rapid use, combined with CPR, as improving the likelihood of restoring circulation. In practice, this makes immediate access to an appropriate defibrillator important during sudden cardiac arrest emergencies.