Centrifugal Pump Bypass
Centrifugal Pump Bypass - Related Videos
08:08
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
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This paper describes how to perform cardiopulmonary bypass in mice. This novel model will facilitate the investigation of the molecular mechanisms involved in organ damage.
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07:37
Roux-en-Y Gastric Bypass Operation in Rats
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07:07
Working with Centrifuges
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2023
Source: Robert M. Rioux & Suprita Jharimune, Pennsylvania State University, University Park, PA Earth's gravitational force is capable of separating heterogeneous mixtures. However, many systems avert this type of separation owing to the length of time usually required in such cases. Centrifugation is one of the most powerful tools for the separation of heterogeneous mixtures1. It involves the application of centripetal force for sedimentation of the heavier phase, leading to separation of...
09:12
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
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Cited by 10 •
2018
This protocol presents a surgical large animal model of chronic, single vessel ischemia that results in regional abnormalities but does not create infarct, known as hibernating myocardium. Following establishment of chronic ischemia, animals are treated with off-pump LIMA-LAD coronary artery bypass graft surgery to revascularize the ischemic tissue.
FAQs
The rotating impeller transfers energy to blood, producing pressure that drives forward flow through the extracorporeal circuit. Increasing or decreasing pump speed changes generated output, but speed alone does not determine circulation. Venous filling and circuit resistance also influence flow, so delivered support must be assessed as a dynamic system.
Flow varies because the pump operates within changing circuit conditions. Pump speed contributes to output, while the amount of venous filling and the resistance encountered by blood alter how much flow the circuit can deliver. This dependence matters clinically because a selected speed should not be interpreted as a guaranteed circulation level.
The system is described as reducing blood stasis, an important circuit-performance feature when blood is circulated outside the body. This characteristic complements active flow generation: the pump supplies forward movement while monitoring confirms that circulation remains appropriate. In cardiac surgery and temporary life support, controlling stasis supports the broader goal of maintaining extracorporeal circulation.
Flow and pressure show whether the circuit is delivering expected circulation, while air surveillance addresses unwanted gas in the circuit. Hemolysis monitoring focuses on this blood-related safety concern, and circuit-performance checks help detect operational problems. Together, these observations provide a safety framework for managing extracorporeal circulation rather than relying on pump speed alone.
It can be used during cardiac surgery when extracorporeal circulation is needed because the heart or lungs cannot provide sufficient flow for the procedure. The pump maintains forward blood movement through the circuit, while flow, pressure, air, hemolysis, and circuit performance are monitored to support controlled surgical circulation.
In extracorporeal membrane oxygenation, the system provides temporary circulatory support for critically ill patients whose heart or lungs cannot provide sufficient flow. Its value lies in maintaining controlled circulation outside the body while clinicians follow circuit flow and pressure and watch for air, hemolysis, or performance problems during support.