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Cardiopulmonary Bypass in a Mouse Model: A Novel Approach
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JoVE Journal Medicine
Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

Cardiopulmonary Bypass in a Mouse Model: A Novel Approach

DOI:
10.3791/56017-v

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08:08 min

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September 22, 2017

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, , , , , , , , , , , , , ,
1Department of Cardiothoracic, Transplantation, and Vascular Surgery,Hannover Medical School, 2Department of Hematology, Oncology, Immunology, Rheumatology, and Pulmonology,University Hospital Tuebingen, 3Department of Pneumology,Hannover Medical School

Chapters

  • 00:05Title
  • 00:50Surgical Equipment Preparations
  • 01:56Surgery: Preparing for the Cardiopulmonary Bypass
  • 04:56Surgery: Cardiopulmonary Bypass Blood Gass Analysis (BGA)
  • 06:25Results: BGA Measurements
  • 07:13Conclusion

Summary

Automatic Translation

Automatic Translation

This paper describes how to perform cardiopulmonary bypass in mice. This novel model will facilitate the investigation of the molecular mechanisms involved in organ damage.

Tags

Keywords: Cardiopulmonary BypassMouse ModelCardiac SurgeryMolecular MechanismsHeart DamageNon-survival Acute ModelVenous CannulaPriming SolutionFemoral ArteryJugular VeinCarotid ArterySilk SuturesMicro Surgical ForcepsBipolar ForcepsCoagulator

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