Fertility-sparing Surgery
Fertility-sparing Surgery - Related Videos
06:24
Fertility Sparing Procedure using Carbon Dioxide Fiber Laser Vaporization of Ovarian Endometrioma
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Cited by 4 •
2022
In this protocol, CO2 fiber laser technique is demonstrated for the surgical treatment of ovarian endometriosis, which represents a viable alternative in terms of fertility preservation with the major advantage of not being dependent on the surgeon's skills and personal experience.
04:34
Modified Spared Nerve Injury Surgery Model of Neuropathic Pain in Mice
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Cited by 5 •
2022
The modified surgery is a simplified method for mouse or rat spared nerve injury model that requires only one ligation and one cut to injure both common peroneal and sural nerves.
01:30
Spare Receptors
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2023
Some receptors remain unoccupied even when an agonist produces a maximal response. Such empty ones are called spare receptors. In presence of spare receptors the maximum effect of an agonist drug is achieved with fewer than 100% of the receptors being occupied. To determine the presence of spare receptors, scientists often compare the concentration of the drug needed to produce 50% of the maximum effect (EC50) with the concentration of the drug needed to occupy 50% of the receptors (Kd). If the...
07:44
The Spared Nerve Injury (SNI) Model of Induced Mechanical Allodynia in Mice
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Cited by 97 •
2011
The Spared Nerve Injury animal model is described here as a mouse model of peripheral neuropathic pain following partial denervation of the sciatic nerve by lesioning the tibial and common peroneal nerve branches, leaving the remaining sural nerve intact. Behavioral modification resulting from mechanical allodynia is quantified by von Frey filaments.
01:38
Fertilization
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2025
During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
FAQs
Suitability depends primarily on the extent of disease, the person’s treatment goals, and reproductive plans. Clinicians must determine whether abnormal tissue can be removed or treated without compromising effective disease management. The decision therefore balances preservation of reproductive potential against the need for adequate treatment, rather than treating fertility preservation as an independent objective.
The reproductive structures retained can influence which aspects of reproductive potential remain available. Keeping the uterus may support the ability to carry a pregnancy, while preserving ovarian tissue may help maintain hormonal function and reproductive potential. Limiting surgery to an affected region can conserve more tissue, but the expected benefit depends on disease extent and individual circumstances.
Fertility preservation cannot replace effective treatment of the underlying disease. Surgical planning must remove or treat abnormal tissue sufficiently while avoiding unnecessary loss of reproductive structures or function. This balance is especially important when disease extent limits what can safely be conserved, because preserving fertility potential is beneficial only when it remains clinically compatible with disease management.
The surgical approach may remove abnormal tissue, treat the affected area, or limit removal to a specific region rather than removing all reproductive structures. The exact plan depends on where and how extensively disease is present. Retaining the uterus or ovarian tissue may be considered when clinically safe, with the goal of conserving relevant reproductive function.
Counseling should address the person’s reproductive plans together with treatment goals and disease-related considerations. This discussion helps clarify which structures or functions might be preserved and what uncertainties remain about future conception or pregnancy. It also supports an individualized decision, since the same surgical strategy may have different significance for people with different family-building plans.
Follow-up evaluates more than the immediate surgical result. Ongoing assessment should consider recurrence risk, hormonal function, and fertility outcomes, because preserving tissue does not guarantee preserved reproductive capability. These measures help clinicians determine whether disease remains controlled and whether the retained reproductive structures continue to support the intended reproductive goals.