Luminal Narrowing Measurement

Luminal narrowing measurement is the quantitative assessment of how much the internal passage, or lumen, of a tubular structure has decreased, a key indicator of stenosis and obstruction in medicine. It works by defining the lumen boundaries on an image or examination, measuring its diameter or cross-sectional area, and comparing the narrowed segment with a nearby normal or reference segment to estimate the degree of reduction. In clinical and research settings, this measurement supports evaluation of blood vessels, airways, and the gastrointestinal tract, helping characterize disease severity, monitor progression or treatment response, and improve consistency when findings are compared across patients or time points.

Luminal Narrowing Measurement - Related Videos

Research

JoVE Journal - Medicine

In Vivo Luminal Measurement of Distension-Evoked Urothelial ATP Release in Rodents

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Cited by 1 •

2022

This protocol describes the procedure for measuring ATP concentrations in the lumen of the bladder in an anesthetized rodent.

Detection of Internal Carotid Artery Narrowing Using Digital Subtraction Angiography

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2025

Position a human patient with internal carotid stenosis, a condition characterized by narrowing of the internal carotid artery, on the imaging table for digital subtraction angiography (DSA). Insert an angiocatheter into the common carotid artery at the fourth cervical vertebra level. Capture a pre-contrast X-ray image to record background structures like bones and soft tissues using X-ray irradiation. Administer an iodine-based contrast medium into the carotid artery. The contrast medium...

Education

JoVE Core - Mechanical Engineering

Distribution of Stresses in a Narrow Rectangular Beam

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2024

In studying beam stress distribution, examining an elemental section is essential. To determine the average shearing stress on this face, the calculated shear is divided by the surface area. Importantly, shearing stresses on the beam's transverse and horizontal planes mirror each other, indicating a consistent stress distribution along the upper region of the beam. Notably, shearing stresses are absent at the beam's upper and lower surfaces due to the absence of applied forces in these areas.

Transfer of Mammary Gland-forming Ability Between Mammary Basal Epithelial Cells and Mammary Luminal Cells via Extracellular Vesicles/Exosomes

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Cited by 8 •

2017

This protocol describes methods for purifying, quantitating, and characterizing extracellular vesicles (EVs)/exosomes from non-adherent/mesenchymal mammary epithelial cells and for using them to transfer mammary gland-forming ability to luminal mammary epithelial cells. EVs/exosomes derived from stem-like mammary epithelial cells can transfer this cell property to cells that ingest the EVs/exosomes.

Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes

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Cited by 2 •

2024

The present protocol describes pH measurements in human tissue-derived gastric organoids using microelectrodes for spatiotemporal characterization of intraluminal physiology.

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