Chemosensory Stimulation

Chemosensory stimulation is the controlled presentation of chemical cues that activate sensory systems for smell, taste, or related chemical detection, allowing researchers to examine how organisms perceive and respond to their environment. In neuroscience experiments, odorants or tastants interact with receptors in the olfactory epithelium or taste buds, triggering neural signals that travel through sensory pathways to the brain. Researchers use these stimuli to investigate perception, sensory coding, learning, memory, motivation, and behavior, while carefully controlling concentration, timing, and delivery. This approach also supports studies of sensory dysfunction and the neural mechanisms underlying chemical communication.

Chemosensory Stimulation - Related Videos

Research

JoVE Journal - Behavior
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Automated Analysis of a Nematode Population-based Chemosensory Preference Assay

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Cited by 3 •

2017

We present a behavior recording setup and protocol that enables automated analysis of the nematode, Caenorhabditis elegans' preference for soluble compounds in a population-based assay. This article describes the construction of a behavior chamber, the behavioral assay protocol, and video analysis software usage.

Research

JoVE Journal - Behavior
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Using Enclosed Y-Mazes to Assess Chemosensory Behavior in Reptiles

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Cited by 3 •

2021

Y-mazes enable researchers to determine the relevance of specific stimuli that drive animal behavior, especially isolated chemical cues from a variety of sources. Careful design and planning can yield robust data (e.g., discrimination, degree of exploration, numerous behaviors). This experimental apparatus can provide powerful insight into behavioral and ecological questions.

Research

JoVE Journal - Neuroscience

Combining Transcranial Magnetic Stimulation and fMRI to Examine the Default Mode Network

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Cited by 17 •

2010

In this article, we examine the methodology and considerations relevant to the combination of TMS and fMRI to examine the effects of brain stimulation on the default network.

Assaying Surface Expression of Chemosensory Receptors in Heterologous Cells

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Cited by 6 •

2011

Here we demonstrate a protocol to carry out live cell staining that can be used to detect odorant receptors on the surface of HEK293T cells conveniently. In addition, it may also be used to assay for surface expression of other chemosensory receptors or GPCRs.

Research

JoVE Journal - Behavior
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Stimulating the Lip Motor Cortex with Transcranial Magnetic Stimulation

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Cited by 29 •

2014

Transcranial magnetic stimulation (TMS) has proven to be a useful tool in investigating the role of the articulatory motor cortex in speech perception. This article describes how to record motor evoked potentials (MEPs) from the lip muscles and how to disrupt the motor lip representation using repetitive TMS.

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