Food Deprivation

Food deprivation is a state in which an organism receives insufficient food or no food for a defined period, altering energy balance and behavior. In neuroscience, reduced nutrient availability changes metabolic signals such as ghrelin, leptin, and insulin, which influence hypothalamic circuits that regulate hunger, energy expenditure, and motivated behavior. These signals also interact with reward and stress pathways, affecting attention, learning, decision-making, and responses to food-related cues. Researchers use controlled food-deprivation paradigms to study feeding regulation, motivation, addiction-related behavior, and the neural consequences of limited energy availability, while carefully considering duration, severity, and animal welfare.

Food Deprivation - Related Videos

Research

JoVE Journal - Neuroscience
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Progressive-ratio Responding for Palatable High-fat and High-sugar Food in Mice

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Cited by 70 •

2012

The present report details the protocol employed to measure the rewarding effects of high-fat food in mice using a progressive ratio operant conditioning task.

Research

JoVE EoE - Neurotherapeutics

Assessing Atmospheric Pressure Plasma Treatment in Glucose-Deprived Neuroblastoma Cells

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2025

Source: Yan, X., et. al., New Application of an Atmospheric Pressure Plasma Jet as a Neuro-protective Agent Against Glucose Deprivation-induced Injury of SH-SY5Y Cells. J. Vis. Exp. (2017)The video demonstrates the neuroprotective activity of low-dose atmospheric pressure plasma treatment in glucose-deprived neuroblastoma cells by modulating oxidative stress and enhancing cell viability.

Education

JoVE Core - Introduction to Psychology

Insufficient Sleep and Sleep Deprivation

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2024

Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being. Sleep deprivation is a more severe form of sleep loss...

Testing For Genetically Modified Foods

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2023

Source: Laboratories of Margaret Workman and Kimberly Frye - Depaul University Genetic modification of foods has been a controversial issue due to debated concerns over health and environmental safety. This experiment demonstrates technical understanding of how food DNA is genetically identified, allowing for educated decision making about the safety and potential dangers of using genetically modified organisms (GMOs) in food supplies. Polymerase Chain Reaction (PCR) is used to amplify food DNA...

A Method for Evaluating the Reinforcing Properties of Ethanol in Rats without Water Deprivation, Saccharin Fading or Extended Access Training

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Cited by 21 •

2017

This protocol describes a novel and efficient method to quickly initiate operant responding for ethanol in rats that, contrary to standard methods, does not require water deprivation or saccharin/sucrose fading to initiate responding.

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