Reversal Trials

Reversal trials are experimental learning trials in which a previously established stimulus-response or stimulus-outcome relationship is changed, allowing researchers to measure how organisms adapt to altered contingencies. During a reversal, feedback signals that the formerly correct choice is no longer rewarded, requiring the participant or animal to suppress the habitual response, update its prediction, and select the alternative. In neuroscience, these trials help quantify cognitive flexibility, reinforcement learning, and error-based updating, while linking behavioral performance to activity in brain systems involved in decision-making and reward. They are useful for studying development, disease-related impairments, and treatment effects.

Reversal Trials - Related Videos

Research

JoVE Journal - Medicine

Reverse Total Shoulder Arthroplasty

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Cited by 5 •

2011

Reverse total shoulder arthroplasty is indicated for the treatment of conditions that cannot be treated with conventional arthroplasty or other procedures. These primarily include degenerative and incapacitating conditions with irreparable rotator cuff and loss of the normal biomechanical coupling of the shoulder.

Education

JoVE Business - Accounting

The Trial Balance

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2025

A trial balance is a fundamental financial statement that provides a snapshot of a company's accounts and their balances at a specific point in time. It serves as an essential tool for verifying the accuracy of financial records by ensuring that the total debits equal the total credits. Typically prepared at the end of an accounting period, a trial balance lists all ledger accounts in the order they appear, with debit balances in the left column and credit balances in the right column. The two...

Clinical Trials

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2023

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias. There are four phases in a clinical trial. A phase one...

Creation of Reversible Cholestatic Rat Model

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2011

Cholestasis is a clinical condition commonly encountered by both surgeons and gastroenterologists. Creation of a reversible cholestatic rat model can be challenging in view of the smaller size and unique hepatopancreatobiliary anatomy in rats. This video article demonstrates the creation of a reversible cholestatic model.

Reversible Cooling-induced Deactivations to Study Cortical Contributions to Obstacle Memory in the Walking Cat

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Cited by 3 •

2017

Complex locomotion in naturalistic environments requiring careful coordination of the limbs involves regions of the parietal cortex. The following protocol describes the use of reversible cooling-induced deactivation to demonstrate the role of parietal area 5 in memory-guided obstacle avoidance in the walking cat.

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