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Biology

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Cell Biology

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Protein Structure

Amyloid Fibrils and Protein Aggregation

Description

Amyloid fibrils are protein aggregates with a very specific structure. They are made when proteins misfold and stick together in long, ordered fibers. This structure makes them different from many other protein clumps.

Amyloid fibrils are important in biology because they are linked to protein ag...

Transcript

Le proteine si ripiegano in strutture energeticamente favorevoli con i loro aminoacidi idrofobi all'interno e gli aminoacidi caricati e polari all'esterno. Alcune proteine si ripiegano facilmente da sole, ma molte sono guidate a ripiegarsi correttamente da proteine chiamate chaperones. A volte le proteine si ripiegano in forme errate, spesso ind...

Tags

Ripiegamento errato delle proteineAggregazione in foglietto betaMalattie prionicheDisturbi neurodegenerativiProteine chaperoneDegradazione proteasomialeFilamento cross betaPlacche amiloidiAmiloidi reversibili

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