Flexible Protein Regions and Disorder

Intrinsically disordered proteins have flexible regions that do not settle into one fixed shape. Instead, these proteins can remain dynamic and change form as they move through the cell. This flexibility is an important part of their structure and function.

Many proteins need a stable folded shap...

Proteins often have rigid secondary and tertiary structures that can be determined experimentally; however, many proteins have flexible structures without a fixed conformation.

These intrinsically disordered proteins, or IDPs, must change shape to perform their functions in an organism. 

Disordered sections of proteins contain many...