3d Optical Scanning

3D optical scanning is a noncontact imaging technique that captures the shape and surface features of an object to create a three-dimensional digital model, supporting precise measurement in bioengineering. The scanner projects structured light or uses multiple camera views to record how light interacts with the target, then computationally reconstructs surface geometry from changes in illumination, perspective, or depth. These models help researchers quantify anatomical structures, characterize biomaterials, assess tissue and organ morphology, and guide the design of custom prostheses, implants, and tissue-engineered constructs. Because scanning preserves complex external geometry without physical contact, it can improve documentation, analysis, and personalized biomedical design.

3d Optical Scanning - Related Videos

Research

JoVE Journal - Neuroscience

A Scanning Electron Microscopy-Compatible Optical Imaging Method for Mesoscopic All-Cell Brain Mapping

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2026

We introduced a novel imaging technique called Optical Multilayer Interference Tomography (OMLIT), which enables unbiased imaging of all cells in brain specimens at the mesoscale and can be seamlessly integrated into the imaging workflow of tape-based serial scanning electron microscopy on the same sample.

Three-dimensional Optical-resolution Photoacoustic Microscopy

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Cited by 27 •

2011

Optical-resolution photoacoustic microscopy (OR-PAM) is an emerging technology capable of imaging optical absorption contrasts in vivo with cellular resolution and sensitivity. Here, we provide a visualized instruction on the experimental protocols of OR-PAM, including system configuration, system alignment, typical in vivo experimental procedures, and functional imaging schemes.

Hand Controlled Manipulation of Single Molecules via a Scanning Probe Microscope with a 3D Virtual Reality Interface

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Cited by 6 •

2016

We demonstrate the precise manipulation of individual organic molecules on a metal surface with the tip of a scanning probe microscope driven in 3D by the experimenter's hand using a motion capture system and fully immersive virtual reality goggles.

In Vivo Imaging of Cx3cr1gfp/gfp Reporter Mice with Spectral-domain Optical Coherence Tomography and Scanning Laser Ophthalmoscopy

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Cited by 5 •

2017

This protocol describes how high-resolution imaging techniques such as spectral domain optical coherence tomography and scanning laser ophthalmoscopy can be utilized in small rodents, using an ophthalmic imaging platform system, to obtain information on retinal thickness and microglial cell distribution, respectively.

Enhanced Communication of Tumor Margins Using 3D Scanning and Mapping

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Cited by 9 •

2023

A novel method for 3D scanning and virtual mapping of cancer resections is proposed with the goal of improving communication among the multidisciplinary cancer care team.

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