Fluid Flow Measurement

Fluid flow measurement is the quantification of how liquids or gases move through a channel, vessel, or device, providing essential information about transport, system performance, and biological function. Measurements typically determine volumetric or mass flow rate by sensing fluid velocity, pressure differences, or changes in fluid properties, with methods such as flow meters, particle tracking, and microfluidic sensors selected according to the flow conditions. In bioengineering, these techniques characterize blood flow, monitor perfusion in engineered tissues, control drug-delivery systems, and evaluate lab-on-a-chip devices. Accurate measurements support safer device design, reproducible experiments, and improved understanding of how fluids influence cells and tissues.

Fluid Flow Measurement - Related Videos

Research

JoVE EoE - Breast Cancer

Spatial Measurement of Tumor Interstitial Fluid Pressure: A Method to Measure the Interstitial Fluid Pressure

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2023

This video describes a technique of measuring the interstitial fluid pressure within a tumor by perfusion imaging using an image-guided robotic system. Measurements are compared to the intra-tumoral accumulation of liposomes, within a solid tumor.

Three-dimensional Cell Culture Model for Measuring the Effects of Interstitial Fluid Flow on Tumor Cell Invasion

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Cited by 13 •

2012

Interstitial fluid flow is elevated in solid tumors and can modulate tumor cell invasion. Here we describe a technique to apply interstitial fluid flow to cells embedded in a matrix and then measure its effects on cell invasion. This technique can be easily adapted to study other systems.

Education

JoVE Science Education - Engineering

Computational Fluid Dynamics Simulations of Blood Flow in a Cerebral Aneurysm

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2023

Source: Joseph C. Muskat, Vitaliy L. Rayz, and Craig J. Goergen, Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana The objective of this video is to describe recent advancements of computational fluid dynamic (CFD) simulations based on patient- or animal-specific vasculature. Here, subject-based vessel segmentations were created, and, using a combination of open-source and commercial tools, a high-resolution numerical solution was determined within a flow model.

Steady Flow of a Fluid Stream

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2024

Consider a control volume, such as a pipe with solid boundaries, through which fluid flows and changes direction due to the impulse exerted by the resulting force from the pipe walls. In steady flow, the mass of fluid entering the control volume at a given time, t, with velocity v1, is equal to the mass leaving after infinitesimal time dt, with velocity v2. During this process, the momentum of the fluid within the control volume remains constant over the time interval dt. By applying the...

Measurement of Fluid Pressure

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2025

Fluid pressure is commonly measured using devices called manometers, which rely on liquid columns to indicate pressure differences. The height of a liquid column in a manometer reflects the pressure exerted by the fluid, providing a simple yet effective means of measurement. Different types of manometers serve specific purposes based on their configurations and the type of fluids involved. A basic form of manometer is the piezometer, a vertical tube open at the top and filled with the same...

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