Inertial Ordering

Inertial ordering is the organization of suspended particles or cells into stable positions or trains as they move through a flowing fluid with appreciable inertia. In microfluidic channels, finite-Reynolds-number flow generates shear-gradient and wall-induced lift forces, while hydrodynamic interactions can align particles and promote ordered spacing; channel geometry and curved-flow effects further influence focusing. In bioengineering, this principle supports label-free cell focusing, sorting, counting, and continuous sample processing. Controlling inertial ordering can improve the uniformity and throughput of microfluidic devices, enabling more precise handling of blood cells, microorganisms, and engineered particles.

Inertial Ordering - Related Videos

Research

JoVE Journal - Bioengineering
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Oscillation and Reaction Board Techniques for Estimating Inertial Properties of a Below-knee Prosthesis

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Cited by 35 •

2014

Body segmental inertial properties are required for inverse dynamics modeling. Using an oscillation and reaction board technique, inertial properties of below-knee prostheses were measured. Using direct measures of prosthesis inertia in the inverse dynamics model of the prosthetic leg resulted in lower magnitudes of resultant joint forces and moments.

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JoVE Core - Physics
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Inertial Frames of Reference

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2023

Newton’s first law is usually considered to be a statement about reference frames. It provides a method for identifying a special type of reference frame: the inertial reference frame. In principle, we can make the net force on a body zero. If its velocity relative to a given frame is constant, then that frame is said to be inertial. So, by definition, an inertial reference frame is a reference frame where Newton's first law holds valid. Newton's first law applies to objects with constant...

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JoVE Core - Physics
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Non-inertial Frames of Reference

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2023

A reference frame accelerating or decelerating relative to an inertial frame is a non-inertial frame. To help understand this, consider what taking off in an airplane, turning a corner in a car, riding a merry-go-round, and the circular motion of a tropical cyclone all have in common. All these systems are accelerating, decelerating, or rotating relative to the Earth; hence, they all are non-inertial frames. All these systems exhibit inertial forces, which merely seem to arise from motion,...

Research

JoVE Journal - Bioengineering

3D Printing of In Vitro Hydrogel Microcarriers by Alternating Viscous-Inertial Force Jetting

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Cited by 5 •

2021

Presented here is a mild 3D printing technique driven by alternating viscous-inertial forces to enable the construction of hydrogel microcarriers. Homemade nozzles offer flexibility, allowing easy replacement for different materials and diameters. Cell binding microcarriers with a diameter of 50-500 µm can be obtained and collected for further culturing.

Label-free Neutrophil Enrichment from Patient-derived Airway Secretion Using Closed-loop Inertial Microfluidics

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Cited by 2 •

2018

In this research, we demonstrate a label-free neutrophil separation method from clinical airway secretions using closed-loop operation of spiral inertial microfluidics. The proposed method would expand the clinical in vitro assays for various respiratory diseases.

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