Vitamin A Deficiency

Vitamin A deficiency is a nutritional disorder in which insufficient vitamin A impairs vision, immune defense, and maintenance of epithelial tissues, making it an important topic in biology and public health. Vitamin A-derived retinoids regulate gene expression and form retinal, a light-sensitive component of visual pigments; inadequate supply disrupts dark adaptation and tissue function. Early signs can include night blindness and dry eyes, while severe deficiency may cause xerophthalmia and increase susceptibility to infection. Studying its causes and effects supports dietary assessment, supplementation, food fortification, and strategies to reduce preventable illness, particularly among children and pregnant individuals.

Vitamin A Deficiency - Related Videos

Education

JoVE Core - Anatomy and Physiology

Vitamins

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2024

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...

Research

JoVE Journal - Bioengineering
Free Sample

PLGA Nanoparticles Formed by Single- or Double-emulsion with Vitamin E-TPGS

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Cited by 211 •

2013

We describe the production and characterization of nanoparticles and microparticles composed of poly(lactic-co-glycolic acid) using vitamin E-TPGS as an emulsifier. By varying formulation parameters such as the concentration of emulsifier, it is possible to produce nanoparticles with mean diameters ranging from 220 nm to 1.98 µm.

A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse

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Cited by 11 •

2016

The following article provides an easy, reproducible technique to effectively create a sustainable mouse model of limbal stem cell deficiency (LSCD). This animal model is useful in testing and comparing the efficacy of treatments for limbal stem cell diseases.

Capital Deficiency in Liquidation: II

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2026

A capital deficiency occurs when a partner's capital account has a debit balance during partnership liquidation. It may result from operating losses, excessive drawings, or losses from the sale of partnership assets. During liquidation, noncash assets are sold, liabilities are paid, gains or losses are allocated to the partners, and the remaining cash is distributed based on the partners' capital balances.Example: Ace Company decides to liquidate because it is nearing bankruptcy. Noncash assets...

No Capital Deficiency in Liquidation

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2026

In accounting, liquidation without capital deficiency is a structured process that enables a partnership to dissolve equitably when partners possess sufficient capital to cover all liabilities and allocated losses. This condition ensures that no partner is required to contribute additional funds to the partnership, streamlining the dissolution procedure.The liquidation process begins with conversion of noncash assets into cash. When these assets are sold, any difference between the sale price...

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