Near Infrared Therapy

Near infrared therapy uses near infrared light to influence biological tissues, making it an important example of how engineered energy-delivery systems can support therapeutic research. Depending on wavelength, power, and exposure time, photons penetrate tissue and may stimulate photobiomodulation by affecting mitochondrial activity, cellular signaling, and local blood flow without relying primarily on heating. Engineering studies focus on designing LED or laser devices, controlling irradiance and treatment geometry, and measuring tissue responses. These systems are investigated for applications including pain management, wound repair, rehabilitation, and neurological research, while careful dosimetry and safety testing help determine their effectiveness and clinical reliability.

Near Infrared Therapy - Related Videos

Education

JoVE Science Education - Chemistry
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Infrared Spectroscopy

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2023

Source: Vy M. Dong and Zhiwei Chen, Department of Chemistry, University of California, Irvine, CA This experiment will demonstrate the use of infrared (IR) spectroscopy (also known as vibrational spectroscopy) to elucidate the identity of an unknown compound by identifying the functional group(s) present. IR spectra will be obtained on an IR spectrometer using the attenuated total reflection (ATR) sampling technique with a neat sample of the unknown.

Research

JoVE EoE - Neurotherapeutics

Modulating Sensory Neuronal Signaling in a Mouse Model Using Near Infrared Light

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2025

Source: Zhang, L., et al. Near Infrared (NIr) Light Increases Expression of a Marker of Mitochondrial Function in the Mouse Vestibular Sensory Epithelium. J. Vis. Exp. (2015)This video demonstrates the process of applying NIr light to a shaved mouse scalp to activate vestibular neurons and stimulate superoxide dismutase-1 (SOD-1) production, supporting neuronal function. The procedure highlights NIr therapy as a neuroprotective strategy.

Characterizing Far-infrared Laser Emissions and the Measurement of Their Frequencies

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Cited by 4 •

2015

We describe the generation of far-infrared radiation using an optically pumped molecular laser along with the measurement of their frequencies with heterodyne techniques. The experimental system and techniques are demonstrated using difluoromethane (CH2F2) as the laser medium whose results include three new laser emissions and eight measured laser frequencies.

Near-infrared Fluorescence Imaging of Abdominal Aortic Aneurysms

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2023

Source: Arvin H. Soepriatna1, Kelsey A. Bullens2, and Craig J. Goergen1 1 Weldon School of Biomedical Engineering, Purdue University, West Lafayette, Indiana 2 Department of Biochemistry, Purdue University, West Lafayette, Indiana Near-infrared fluorescence (NIRF) imaging is an exciting optical technique that utilizes fluorescent probes to visualize complex biomolecular assemblies in tissues. NIRF imaging has many advantages over conventional imaging methods for noninvasive imaging of diseases.

Visualization of Mouse Cerebral Thrombi Using Near-Infrared Fluorescence Imaging

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2025

Source: Kim, D. E., et al. Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli. J. Vis. Exp. (2016)This video demonstrates near-infrared fluorescent (NIRF) imaging to visualize thrombi in excised brain tissue labeled with a fibrin-specific probe. Near-infrared light excites the probe, causing the thrombus to fluoresce, enabling high-contrast thrombi visualization in the major cerebral artery and small cortical blood vessels.

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