Handheld Ultrasonicator
Handheld Ultrasonicator - Related Videos
09:25
Assessment of Ultrasonic Vocalizations During Drug Self-administration in Rats
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Cited by 17 •
2010
Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.
11:00
Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats
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Cited by 31 •
2011
Voice disorders are debilitating in aging and Parkinson disease. The ultrasonic vocalizations of rats, also affected by these conditions, can be used to study these voice disorders, their neural substrates, and the nature of functional recovery with behavioral intervention.
09:21
Experiments on Ultrasonic Lubrication Using a Piezoelectrically-assisted Tribometer and Optical Profilometer
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Cited by 3 •
2015
We present a protocol for using a piezoelectrically-assisted tribometer and optical profilometer to investigate the dependence of ultrasonic wear and friction reduction on linear velocity, contact pressure, and surface properties.
10:28
Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication
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Cited by 80 •
2016
Mouse ultrasonic vocalizations are used as proxies to model the genetic bases of vocal communication deficits in mouse models for neuropsychiatric disorders. The present protocol describes three experimental contexts that reliably elicit ultrasonic vocalizations from pups (throughout development) and adult mice (same-sex interactions, male-estrus female interactions).
05:40
Handheld Device for Saliva Pretreatment to Improve Cortisol Detection
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2026
This protocol describes a rapid saliva pretreatment method for improving cortisol detection. A handheld filtration device is used to remove mucins and other interfering substances while preserving the target analyte. The pretreated saliva exhibits improved capillary flow, thereby enabling more consistent and reproducible assay performance.
FAQs
Cavitation creates bubbles that rapidly form and collapse within the liquid. Their collapse produces intense, localized forces that break up suspended material and promote contact between the liquid and sample components. In environmental preparations, this action can help release analytes from soil or sediment into the liquid phase, making them more accessible for subsequent chemical analysis.
The piezoelectric transducer is the energy-conversion component: it changes electrical energy into mechanical vibrations. The probe transfers those vibrations into the liquid, where they generate the cavitation responsible for sample disruption and mixing. This arrangement concentrates ultrasonic energy at the sample rather than relying only on general movement of the surrounding liquid.
The localized forces generated during treatment can disperse suspended particles, disrupt cells, and homogenize a sample. These effects are useful because environmental materials may contain analytes associated with particles or biological material. By making the sample more uniform and exposing additional material to the liquid, treatment can support more consistent preparation for chemical measurements.
A basic workflow begins with a liquid preparation containing the environmental material of interest, such as water, soil-derived material, or sediment-derived material. The probe is introduced into the sample and ultrasonic energy is applied to disrupt, disperse, or homogenize it. The treated preparation can then be used for analyte release and subsequent chemical analysis.
Researchers may choose this device when sample preparation must support contaminant monitoring, chemical analysis, or field-oriented environmental research. Its portable format is especially relevant when treatment needs to be performed close to sampling activities rather than only in a fixed laboratory. The method helps prepare environmental liquids and material-derived samples for analysis by improving dispersion or analyte release.
Ultrasonic treatment does not itself identify a contaminant, but it can improve access to analytes before measurement. By dispersing particles, homogenizing preparations, or releasing analytes from soil and sediment, it supports the sample-preparation stage of chemical analysis. The resulting preparation can therefore contribute to investigations of contaminants in water and other environmental materials.