Ultra-clean Sampling

Ultra-clean sampling is a contamination-control approach for collecting environmental samples when target substances occur at very low concentrations, making it essential for reliable trace-level measurements. It works by separating clean and potentially contaminated activities, using rigorously cleaned or disposable equipment, minimizing sample exposure, and preserving samples under controlled conditions from collection through analysis. Field blanks, equipment blanks, documented handling procedures, and chain-of-custody records help identify contamination introduced during sampling or transport. In environmental research and monitoring, these practices improve data quality and support defensible assessments of water, soil, sediment, and other media, particularly when results inform regulatory decisions or long-term pollution studies.

Ultra-clean Sampling - Related Videos

Research

JoVE Journal - Biology

MALDI Sample Preparation: the Ultra Thin Layer Method

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Cited by 32 •

2007

This video demonstrates the preparation of an ultra-thin matrix/analyte layer for analyzing peptides and proteins by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS).

Clean Sampling and Analysis of River and Estuarine Waters for Trace Metal Studies

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Cited by 3 •

2016

Special care using "clean techniques" is required to properly collect and process water samples for trace metal studies in aquatic environments. A protocol for sampling, processing, and analytical procedures with the aim of obtaining reliable environmental monitoring data and results with high sensitivity for detailed trace metal studies is presented.

Education

JoVE Science Education - Chemistry

Cleaning Glassware

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2023

Source: Vy M. Dong and Daniel Kim, Department of Chemistry, University of California, Irvine, CA Organic synthesis is about transforming a readily available reagent into a more valuable product. Having clean glassware is crucial for the efficiency of this process. Dirty glassware can potentially affect the reaction and make isolation of the final product more challenging. Thus, a synthetic chemist must keep the glassware spotless. The methods described here will detail different glass cleaning...

An Ultra-clean Multilayer Apparatus for Collecting Size Fractionated Marine Plankton and Suspended Particles

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Cited by 6 •

2018

Plankton and suspended particles play a major role in the biogeochemical cycles in the ocean. Here, we provide an ultra-clean, low stress method for the collection of various sizes of particles and plankton at sea with the capability of handling large volumes of seawater.

Research

JoVE Journal - Biology
Free Sample

Proper Care and Cleaning of the Microscope

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Cited by 2 •

2008

Keeping the microscope optics clean is important for high-quality imaging. Dust, fingerprints, excess immersion oil, or mounting medium on or in a microscope causes reduction in contrast and resolution. DIC is especially sensitive to contamination and scratches on the lens surfaces. This protocol details the procedure for keeping the microscope clean.

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