Internal Mammary Vein

The internal mammary vein, also called the internal thoracic vein, is a paired vessel that returns deoxygenated blood from the anterior chest wall, breast, and upper abdominal wall to the central venous circulation. It generally accompanies the internal thoracic artery along the inner surface of the sternum, receives tributaries from intercostal and perforating veins, and typically joins the corresponding brachiocephalic vein. Understanding its course and drainage territory supports clinical anatomy, breast and chest wall surgery, vascular imaging, and procedures involving internal thoracic vessels. Its proximity to the sternum also makes it relevant during thoracic operations and assessment of venous injury.

Internal Mammary Vein - Related Videos

Research

JoVE Journal - Developmental Biology

Transfer of Mammary Gland-forming Ability Between Mammary Basal Epithelial Cells and Mammary Luminal Cells via Extracellular Vesicles/Exosomes

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Cited by 8 •

2017

This protocol describes methods for purifying, quantitating, and characterizing extracellular vesicles (EVs)/exosomes from non-adherent/mesenchymal mammary epithelial cells and for using them to transfer mammary gland-forming ability to luminal mammary epithelial cells. EVs/exosomes derived from stem-like mammary epithelial cells can transfer this cell property to cells that ingest the EVs/exosomes.

Portal Vein Injection: A Method to Study Cancer Metastasis to the Liver

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2023

This video describes a surgical procedure to deliver mammary tumor cells to the murine liver via portal vein injection. This model permits the investigation of late stages of liver metastasis.

Intraductal Delivery to the Rabbit Mammary Gland

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Cited by 9 •

2017

Here, we describe a technique for the localized delivery of reagents to the rabbit mammary gland via an intraductal injection. In addition, we describe a protocol for visualization and the confirmation of delivery by high-resolution ultrasound imaging of contrast agents.

Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis

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Cited by 5 •

2012

This video shows a model to study the development of intimal hyperplasia after stent deployment using a human vessel (IMA) in an immunodeficient rat model.

Decellularizing Mammary Fat Pads: Deriving Extracellular Matrix Hydrogels from Mammary Fat Pads

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2023

This video describes a technique of deriving extracellular matrix hydrogels by decellularizing murine mammary fat pads following ex vivo irradiation for in vitro studies. This hydrogel helps to mimic the in vivo breast tissue environment post-radiation treatment to study tumor cell behavior.

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