Thermodilution

Thermodilution is a physiological measurement technique that estimates blood flow, most commonly cardiac output, by tracking how an injected temperature indicator disperses through the circulation. In conventional pulmonary artery thermodilution, a known volume of cool fluid enters the right atrium, mixes with blood, and produces a temperature change detected downstream; the Stewart-Hamilton principle relates the resulting temperature-time curve to flow. Clinicians use thermodilution during hemodynamic assessment, particularly in critically ill patients, to evaluate cardiac performance and guide treatment. Transpulmonary approaches can also provide estimates of cardiac output and related circulatory variables without placing a catheter in the pulmonary artery.

Thermodilution - Related Videos

Education

JoVE Science Education - Clinical Skills

COVID-19 / Coronavirus Outbreak: Hemodynamic monitoring with PiCCO artery

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2020

During pandemics, medical staff become a key resource in treating and managing patients with these infectious diseases. To achieve the best medical care, relevant techniques and procedures must be taught to medical staff which minimize the risk of work-related transmission of infection. When carrying out hemodynamic monitoring in cardiovascularly unstable patients, it is possible to utilize a Pulse Contour Cardiac Output (PiCCO) catheter. This system utilizes a thermodilution method to analyze...

Research

JoVE Journal - Medicine

Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)

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Cited by 21 •

2016

Repeated pulmonary lavages in anesthetized pigs induce lung injury resembling major aspects of human acute respiratory distress syndrome (ARDS). For this purpose the lungs are repeatedly lavaged with 0.9% saline at 37 °C. The goal of the protocol is a reproducible mitigation of gas exchange and hemodynamics for research in ARDS.

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