Symmetric Asymmetric Division

Symmetric and asymmetric division are patterns of cell division that determine whether daughter cells share the same fate or adopt different identities. In symmetric division, a progenitor produces equivalent daughter cells, supporting population expansion; in asymmetric division, unequal segregation of cell components, fate determinants, or signaling activity generates distinct daughter-cell outcomes. In neuroscience, neural stem and progenitor cells use these strategies to balance self-renewal with the production of neurons and glial cells during development. Understanding this balance clarifies how neural tissues grow, organize, and maintain cellular diversity, while revealing mechanisms that may contribute to neurodevelopmental disorders and brain regeneration.

Symmetric Asymmetric Division - Related Videos

Research

JoVE Journal - Chemistry
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Phase Behavior of Charged Vesicles Under Symmetric and Asymmetric Solution Conditions Monitored with Fluorescence Microscopy

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Cited by 20 •

2017

Experiments on phase separated giant unilamellar vesicles (GUVs) frequently neglect physiological solution conditions. This work presents approaches to study the effect of high-salinity buffer on liquid-liquid phase separation in charged multicomponent GUVs as a function of trans-membrane solution asymmetry and temperature.

Education

JoVE Core - Analytical Chemistry

IR Spectrum Peak Splitting: Symmetric vs Asymmetric Vibrations

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2024

Identical bonds within a polyatomic group can stretch symmetrically (in-phase) or asymmetrically (out-of-phase). Similar to hydrogen bonding, these vibrations also influence the shape of the IR peak. Generally, asymmetric stretching frequencies are higher than symmetric stretching frequencies. For example, primary amines exhibit two distinct IR peaks between 3300–3500 cm−1 corresponding to the symmetric and asymmetric N-H stretching, while secondary amines exhibit a single stretching vibration...

Asymmetric Walkway: A Novel Behavioral Assay for Studying Asymmetric Locomotion

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Cited by 4 •

2016

Here, we present a protocol to quantify precise stepping in rodents. Cortical and the spinal central pattern generator signals are required for precise foot-placement during obstructed locomotion. We report here the novel constrained walking task that directly examines precise stepping behavior.

Cell Division - Concepts

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2019

Cell division is fundamental to all living organisms and required for growth and development. As an essential means of reproduction for all living things, cell division allows organisms to transfer their genetic material to their offspring. For a unicellular organism, cellular division generates a completely new organism. For multicellular organisms, cellular division produces new cells for the general development of the organism, as well as produces healthy cells to replace damaged cells from...

Cell Division - Student Protocol

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2019

Observing the Cell Cycle in a Root Tip ExpandHypotheses: The experimental hypothesis is that in root tips slices that have been treated with nocodazole, a chemical that interferes with microtubular polymerization, all of the cells will be arrested at the same stage of the cell cycle and that in untreated onion tip slices all of the different stages of the cell cycle will be visualized. The null hypothesis is that there will be no differences in mitosis between the two groups and that different...

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