Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Alba C. de Luca; Alessandro Faroni; Adam J. Reid

doi:10.3791/52543

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Gangli neuroni e cellule staminali derivate da tessuto adiposo differenziata: An In Vitro Co-coltura modello per studiare Peripheral Nerve Regeneration

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An <em>In Vitro</em> Co-culture Model to Study Peripheral Nerve Regeneration

JoVE Journal
Neuroscienze

This content is Free Access.

JoVE Journal Neuroscienze

Dorsal Root Ganglia Neurons and Differentiated Adipose-derived Stem Cells: An In Vitro Co-culture Model to Study Peripheral Nerve Regeneration

Gangli neuroni e cellule staminali derivate da tessuto adiposo differenziata: An In Vitro Co-coltura modello per studiare Peripheral Nerve Regeneration

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21,223 Views

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09:17 min

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February 26, 2015

DOI:

10.3791/52543-v

DOI:

10.3791/52543-v

•

09:17 min

February 26, 2015

•

52 Views

Alba C. de Luca¹, Alessandro Faroni², Adam J. Reid^2,3

¹Centre for Neuroprosthesis,EPFL | STI | IMT/IBI | LSBI, ²Blond McIndoe Research Laboratories, Institute of Inflammation & Repair,The University of Manchester, ³University Hospital of South Manchester

Summary

Gangli spinali (DRG) sono strutture che contengono i neuroni sensoriali del sistema nervoso periferico. Quando dissociato, possono essere co-coltura con cellule staminali derivate da tessuto adiposo SC-like (ASC), che fornisce un modello valido per lo studio in vitro rigenerazione e mielinizzazione nervo, imitando l'ambiente in vivo presso il sito di lesione.