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Forward Genetica schermi usando macrofagi per identificare<em> Toxoplasma gondii</em> geni importanti per la Resistenza di IFN-γ-Dependent cellulare Immunità autonoma
Forward Genetics Screens Using Macrophages to Identify <em>Toxoplasma gondii </em>Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
JoVE Journal
Immunologia e infezioni
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JoVE Journal Immunologia e infezioni
Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Forward Genetica schermi usando macrofagi per identificare<em> Toxoplasma gondii</em> geni importanti per la Resistenza di IFN-γ-Dependent cellulare Immunità autonoma

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11:21 min

March 12, 2015

DOI:

11:21 min
March 12, 2015

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Summary

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Forward genetics is a powerful approach to identify genes in intracellular pathogens important for resistance to cell autonomous immunity. The current approach uses innate immune cells, specifically macrophages, to identify novel Toxoplasma gondii genes important for immune evasion.

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