Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / A 3D Human Lung Tissue Model for Functional…
JoVE Journal
Immunology and Infection

This Contenuto is Open Access.

JoVE Journal Immunology and Infection
A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
Influenza Virus Propagation in Embryonated Chicken Eggs
Journal (Immunology and Infection)
Influenza Virus Propagation in Embryonated Chicken Eggs
Laminar Flow-based Assays to Investigate Leukocyte Recruitment on Cultured Vascular Cells and Adherent Platelets
Journal (Immunology and Infection)
Laminar Flow-based Assays to Investigate Leukocyte Recruitment on Cultured Vascular Cells and Adherent Platelets
 

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Article DOI: 10.3791/53084-v • 10:10 min • October 5th, 2015
October 5th, 2015 •
1, 2, 2, 1, 1,2
1Department of Clinical and Experimental Medicine, Linköping University, 2Department of Medicine, Karolinska Institute

Capitoli

Riepilogo
Automatic Translation

Human tuberculosis infection is a complex process, which is difficult to model in vitro. Here we describe a novel 3D human lung tissue model that recapitulates the dynamics that occur during infection, including the migration of immune cells and early granuloma formation in a physiological environment.

Tags

3D Human Lung Tissue Model Mycobacterium Tuberculosis Infection Tuberculosis In Vitro Model Disease Mechanisms Treatment Options Epithelial Cells Fibroblasts Collagen Matrix Porous Membrane Mucus Secretion Primary Macrophages TB Granuloma Organotypic Culture Method Host Cell-pathogen Interactions
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter