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Immunology and Infection

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Productie van menselijke CRISPR-engineered CAR-T-cellen

Article DOI: 10.3791/62299-v • 06:33 min • March 15th, 2021
March 15th, 2021 •
*1,2, *1,2, 1,2, 1,2
1Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, 2Parker Institute for Cancer Immunotherapy, University of Pennsylvania
* These authors contributed equally

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Hier presenteren we een protocol voor genbewerking in primaire menselijke T-cellen met behulp van CRISPR Cas-technologie om CAR-T-cellen te wijzigen.

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Immunologie en infectie Chimeric Antigen Receptor (CAR)-T cellen cellulaire immunotherapie gentherapie lentivirale vector genbewerking CRISPR/Cas9 T lymfocyten
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