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Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Article DOI: 10.3791/63508-v • 10:18 min • February 1st, 2022
February 1st, 2022 •
1, 2, 2, 1, 1, 2, 3
1The First Clinical College of Dalian Medical University, 2Department of Cardiology, State Key Laboratory of Organ Failure Research, Nanfang Hospital, Southern Medical University, 3College of Pharmacy, Dalian Medical University

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There are several differences between the right and left ventricles. However, the pathophysiology of right ventricular infarction (RVI) has not been clarified. In the present protocol, a reproducible method for RVI mouse model generation is introduced, which may provide a means to explain the mechanism of RVI.

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Right Ventricular Myocardial Infarction Permanent Ligation Right Coronary Artery Mice Model Pathophysiological Mechanism Infarction Model Procedure Anesthesia Electrocardiography Chest Incision Pectoralis Muscles
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