Waiting
Elaborazione accesso...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / Modeling Oral-Esophageal Squamous Cell Carcinoma…
JoVE Journal
Cancer Research

È necessario avere un abbonamento a JoVE per visualizzare questo Contenuto. Accedi o inizia la tua prova gratuita.

JoVE Journal Cancer Research
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
A Syngeneic Pancreatic Cancer Mouse Model to Study the Effects of Irreversible Electroporation
Journal (Cancer Research)
A Syngeneic Pancreatic Cancer Mouse Model to Study the Effects of Irreversible Electroporation
Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases
Journal (Cancer Research)
Evaluation of the Feasibility, Safety, and Accuracy of an Intraoperative High-intensity Focused Ultrasound Device for Treating Liver Metastases
 

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Article DOI: 10.3791/64676-v • 10:43 min • December 23rd, 2022
December 23rd, 2022 •
*1, *1,2, 1, 1, 1, 1, 1, 1,3, 1,3, 4, 1,2, 1,5, 1,6, 1,7, 1,5, 1,2,5
1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University
* These authors contributed equally

Capitoli

Riepilogo
Automatic Translation

This protocol describes the key steps to generate and characterize murine oral-esophageal 3D organoids that represent normal, preneoplastic, and squamous cell carcinoma lesions induced via chemical carcinogenesis.

Tags

Modeling Oral-esophageal Squamous Cell Carcinoma 3D Organoids ESCC Molecular Changes Genetic Heterogeneity Mutagen-induced Tumors Therapeutic Strategies Genetic Changes Tumorigenesis Animal Dissection Organ Collection Skin Incision Cervical Trachea Thoracic Trachea Peritoneum
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter