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En silikosmusmodell som fastställts genom upprepad inandning av kristallint kvartsdamm

Article DOI: 10.3791/64862-v • 10:45 min • January 6th, 2023
January 6th, 2023 •
*1,2,3,4, *1,2,3,4, 1,3,4, 1,4, 1,4, 1,4, 1,2,3,4, 1,2,3,4
1Key Laboratory of Industrial Dust Control and Occupational Health of the Ministry of Education, Anhui University of Science and Technology, 2Key Laboratory of Industrial Dust Deep Reduction and Occupational Health and Safety of Anhui Higher Education Institutes, Anhui University of Science and Technology, 3Anhui Province Engineering Laboratory of Occupational Health and Safety, 4School of Medicine, Department of Medical Frontier Experimental Center, Anhui University of Science and Technology
* These authors contributed equally

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Detta protokoll beskriver en metod för att etablera en musmodell av silikos genom upprepad exponering för kiseldioxidsuspensioner via ett näsdropp. Denna modell kan effektivt, bekvämt och flexibelt efterlikna den patologiska processen för human silikos med hög repeterbarhet och ekonomi.

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Medicin Utgåva 191 Musmodell Inandning Patofysiologi Screening Behandling Kliniska symtom Akut/kronisk transformationsprocess Procedurer CSD-pulver Saltlösningssuspension Ultraljudsvattenbad Anestesi Aspiration Inandning av näsborrar Musbur
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