Terapia sonodinamica per il trattamento del glioblastoma multiforme in un modello murino utilizzando un sistema portatile ad ultrasuoni focalizzato da banco
4.7K visualizzazioni
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Citato da 5
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09:07 min.
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10 febbraio 2023
DOI :10.3791/65114-v
10 febbraio 2023
•4.7K visualizzazioni
Griffin Mess1,2 , Taylor Anderson1,2 , Shivani Kapoor3 , Rasika Thombre1,2 , Ruixing Liang4 , Emre Derin1 , Kelley M. Kempski-Leadingham1 , Santosh K. Yadav5 , Betty Tyler1 , Amir Manbachi1,2,4,6,7
1Department of Neurosurgery, Johns Hopkins University School of Medicine, 2Department of Biomedical Engineering, Johns Hopkins University, 3Krieger School of Arts and Sciences, Johns Hopkins University, 4Department of Electrical Engineering and Computer Science, Johns Hopkins University, 5Department of Radiology, Cancer Imaging Division, Johns Hopkins University School of Medicine, 6Department of Mechanical Engineering, Johns Hopkins University, 7Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine
Qui, descriviamo un protocollo che descrive in dettaglio come eseguire la terapia sonodinamica in un modello di glioblastoma murino in vivo utilizzando ultrasuoni focalizzati guidati dalla risonanza magnetica.
Chapters in this video
0:04
Introduction
1:31
Animal Preparation for Sonodynamic Therapy (SDT)
2:42
MRI Procedures
5:42
Focused Ultrasound Treatment
7:34
Results: Reduction in Tumor Size After SDT Treatment in Animals with GBM Tumors
8:15
Conclusion
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