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Immunology and Infection

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Cell-Based Electrical Impedance Platform to Evaluate Zika Virus Inhibitors in Real Time
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Cell-Based Electrical Impedance Platform to Evaluate Zika Virus Inhibitors in Real Time

Article DOI: 10.3791/65149-v • 05:49 min • March 24th, 2023
March 24th, 2023 •
1, 1, 1
1Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, KU Leuven

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Here, we demonstrate the use of cell-based electrical impedance (CEI) as a very easy and straightforward method to study Zika virus infection and replication in human cells in real time. Furthermore, the CEI assay is useful for the evaluation of antiviral compounds.

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Cell-based Electrical Impedance Zika Virus Inhibitors Real-time Evaluation Viral Infections Endpoint Assays Antiviral Compounds CEI Plate Interdigitated Electrode-based 96 Well Plate Growth Culture Medium A549 Cells Cell Density CEI Device CEI Assay Data Collection
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