Transcatheter Delivery
Transcatheter Delivery - Related Videos
07:46
Automatic Surgery in Transcatheter Aortic Valve Replacement Using Augmented Reality
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Cited by 2 •
2024
This article presents the design and implementation of an automatic surgery module based on augmented reality (AR)- based 3D reconstruction. The system enables remote surgery by allowing surgeons to inspect reconstructed features and replicate surgical hand movements as if they were performing the surgery in close proximity.
07:41
Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
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Cited by 4 •
2022
Transthoracic (TTE) and transesophageal (TEE) echocardiography represent the basic imaging tools for interatrial septum examination. Three dimensional (3D) TEE provides incremental information in the assessment of the interatrial septum. Further advanced echocardiography techniques using speckle tracking echocardiography are applied for sensitive volumetric and functional assessment of the heart...
05:31
Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
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Cited by 4 •
2022
This study demonstrates the feasibility and safety of developing an autologous pulmonary valve for implantation at the native pulmonary valve position by using a self-expandable Nitinol stent in an adult sheep model. This is a step toward developing transcatheter pulmonary valve replacement for patients with right ventricular outflow tract dysfunction.
06:30
Intraductal Delivery to the Rabbit Mammary Gland
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Cited by 9 •
2017
Here, we describe a technique for the localized delivery of reagents to the rabbit mammary gland via an intraductal injection. In addition, we describe a protocol for visualization and the confirmation of delivery by high-resolution ultrasound imaging of contrast agents.
08:02
Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
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Cited by 40 •
2013
Rapid mechanical deformation of cells has emerged as a promising, vector-free method for intracellular delivery of macromolecules and nanomaterials. This protocol provides detailed steps on how to use the system for a broad range of applications.
FAQs
Flexibility allows a catheter to follow curved blood vessels or other body passages, while steerable designs help engineers direct its tip toward the intended site. These features support precise navigation and can help reach anatomically difficult locations. In engineering terms, catheter geometry and controllability are central to balancing access with delivery accuracy.
Controlled release or deployment determines how the payload becomes available after the catheter reaches its target. A therapeutic agent may be released, whereas an implant, stent, embolic material, or other device may be deployed in position. Separating navigation from the final release or deployment step helps match the delivery mechanism to the intended intervention and anatomical site.
Biomaterials and imaging integration address different engineering challenges. Biomaterials support the design of catheters and delivered products, while imaging integration assists with locating and guiding the system during an intervention. Together, they can improve treatment accuracy and support safer access to difficult-to-reach tissues, linking material selection with procedural control.
The process begins by guiding the catheter through a blood vessel or other body passage toward a selected anatomical site. Once positioned, the system delivers or deploys the intended agent, implant, or device using an appropriate release or deployment mechanism. The sequence therefore combines navigation, target positioning, and controlled transfer of the therapeutic product.
The approach can transport several categories of therapeutic products, including drugs, stents, embolic materials, tissue-engineering products, and other medical devices. Engineering design depends on whether the payload must be released as an agent or positioned as an implant or device. This range allows the technique to support distinct cardiovascular and other medical interventions.
It is particularly relevant when treatment must reach a targeted anatomical site while limiting the trauma associated with more invasive surgery. Cardiovascular interventions are a major application, and the same strategy also supports other medical procedures involving difficult-to-reach tissues. Its value depends on accuracy, safety, access, and the suitability of the delivery mechanism for the intended product.