Ards Case
Ards Case - Related Videos
07:20
Lavage-induced Surfactant Depletion in Pigs As a Model of the Acute Respiratory Distress Syndrome (ARDS)
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Cited by 21 •
2016
Repeated pulmonary lavages in anesthetized pigs induce lung injury resembling major aspects of human acute respiratory distress syndrome (ARDS). For this purpose the lungs are repeatedly lavaged with 0.9% saline at 37 °C. The goal of the protocol is a reproducible mitigation of gas exchange and hemodynamics for research in ARDS.
08:22
The Application of Point-of-Care Ultrasonography (POCUS) in the Management of Acute Respiratory Distress Syndrome (ARDS) in the Intensive Care Unit
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2025
Here, we present a protocol for bedside POCUS application in ARDS management within the ICU. It details standardized techniques for lung, cardiac, diaphragm, venous, and gastric assessments to guide ventilation, predict weaning, and prevent complications.
08:12
Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
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Cited by 5 •
2018
We present a protocol of creating right ventricular dysfunction in a pig model by inducing ARDS. We demonstrate invasive monitoring of left and right ventricular cardiac output using flow probes around the aorta and the pulmonary artery, as well as blood pressure measurements in the aorta and pulmonary artery.
06:22
Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
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Cited by 5 •
2021
A combination of surfactant washout using 0.9% saline (35 mL/kg body weight, 37 °C) and high tidal volume ventilation with low PEEP to cause moderate ventilator induced lung injury (VILI) results in experimental acute respiratory distress syndrome (ARDS). This method provides a model of lung injury with low/limited recruitability to study the effect of various ventilation strategies for extended periods.
13:44
Haptic/Graphic Rehabilitation: Integrating a Robot into a Virtual Environment Library and Applying it to Stroke Therapy
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Cited by 8 •
2011
Recently, a vast amount of prospects have come available for human-robot interactive systems. In this paper we outline the integration of a new robotic device with open source software that can rapidly make possible a library of interactive functionality. We then outline a clinical application for a neurorehabilitation application.
FAQs
Damage to the alveolar-capillary barrier is the central event. Once that barrier becomes permeable, protein-rich fluid moves into the alveoli, where it interferes with the air-space environment needed for oxygen transfer. In an ARDS case, this mechanism explains why severe hypoxemia can persist even when supplemental oxygen is provided.
Reduced lung compliance is a functional consequence of fluid accumulation and diffuse pulmonary inflammation. The lungs become harder to expand, while affected alveoli transfer oxygen less effectively. Interpreting these linked findings helps connect respiratory difficulty, blood-gas abnormalities, and oxygenation results to acute lung injury rather than viewing each clinical finding in isolation.
An ARDS case must be distinguished from cardiogenic pulmonary edema and other causes of respiratory failure. The comparison uses the full clinical pattern, including risk factors, symptoms, imaging, blood-gas findings, and oxygenation measures. This structured differential assessment is important because similar respiratory findings may arise through different mechanisms and require different clinical reasoning.
The severity of hypoxemia is interpreted alongside imaging and clinical context rather than in isolation. Combining oxygenation measures with blood-gas findings helps clinicians assess whether the case fits ARDS diagnostic criteria. Symptoms and risk factors then establish the acute clinical context, strengthening the connection between objective respiratory abnormalities and the suspected lung injury.
Begin by integrating symptoms and relevant risk factors, then review imaging, blood-gas findings, and oxygenation measures. Next, compare the overall pattern with diagnostic criteria and consider cardiogenic pulmonary edema or other causes of respiratory failure. This sequence turns scattered clinical data into a structured case assessment and supports timely management decisions.
Management centers on lung-protective ventilation while clinicians address the underlying cause. The ventilation strategy supports gas exchange while limiting additional stress on already injured lungs, and treatment of the precipitating condition targets the source of injury. In case-based medicine, keeping these priorities together prevents respiratory support from replacing cause-directed care.
Following an ARDS case over time helps clinicians recognize complications and judge whether respiratory failure is improving or worsening. Reassessment should connect changes in symptoms, imaging, blood-gas findings, and oxygenation measures with the clinical response. This longitudinal approach is more informative than relying on a single measurement and supports adjustment of treatment as the case evolves.