Atrial Fibrillation

Atrial fibrillation is the most common sustained cardiac arrhythmia, characterized by rapid, irregular activation of the atria that disrupts coordinated contraction and can impair cardiac function. Disorganized electrical impulses, often arising near the pulmonary veins, cause the atria to quiver while the atrioventricular node conducts an irregular pattern of impulses to the ventricles. This loss of effective atrial contraction can promote blood stasis and clot formation, increasing the risk of ischemic stroke, while a persistently rapid ventricular response may contribute to heart failure. Clinical evaluation guides rhythm or rate control, anticoagulation, and catheter ablation, making atrial fibrillation a major focus of cardiovascular medicine.

Atrial Fibrillation - Related Videos

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JoVE Journal - Medicine
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Robotic Ablation of Atrial Fibrillation

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Cited by 12 •

2015

Pulmonary vein isolation (PVI) with an ablation catheter is a curative treatment for atrial fibrillation (AF). Robotic catheter systems aim to improve catheter steerability. Here, a procedure with a new robotic catheter system is presented. The goal of the procedure is electrical block between pulmonary vein and left atrium.

Research

JoVE Journal - Medicine
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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

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Cited by 11 •

2013

Catheter ablation is combined with placement of the WATCHMAN Left Atrial Appendage Closure Device to prevent ischemic stroke in a patient with non-valvular atrial fibrillation.

Research

JoVE Journal - Medicine
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The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation

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Cited by 49 •

2012

The accompanying video describes a procedure for percutaneous placement of the WATCHMAN Left Atrial Appendage (LAA) Device. The WATCHMAN is a nitinol device designed to be permanently implanted at, or slightly distal to, the opening of the left atrial appendage (LAA) to trap blood clots before they exit the LAA, preventing thromboembolic stroke.

Research

JoVE Journal - Medicine

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation

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Cited by 20 •

2011

This report provides a detailed description of the methodology and results of simultaneous endocardial and epicardial optical mapping of electrical excitation in the intact left atrium of a Langendorff-perfused sheep heart during stretch-induced atrial fibrillation.

Transesophageal Atrial Burst Pacing for Atrial Fibrillation Induction in Rats

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Cited by 6 •

2022

The present work describes an experimental protocol of transesophageal atrial burst pacing for efficient induction of atrial fibrillation (AF) in rats. The protocol can be used in rats with healthy or remodeled hearts, allowing the study of AF pathophysiology, identification of novel therapeutic targets, and evaluation of new therapeutic strategies.

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