Inverse Geometry Imaging

Inverse geometry imaging is a medical radiographic approach that reverses the usual relationship between the X-ray source and detector to capture projection data efficiently. In this configuration, a distributed or scanning source illuminates different regions of the patient, while a relatively small detector records transmitted signals; computational reconstruction then combines these measurements from multiple positions to estimate internal anatomy. This design can support computed tomography and other medical imaging systems, potentially improving temporal resolution, detector utilization, or dose efficiency. It also provides a framework for studying sampling geometry, artifacts, and image quality.

Inverse Geometry Imaging - Related Videos

Education

JoVE Core - Chemistry

Coordination Number and Geometry

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2020

For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar. Coordination Number Molecular Geometry Example 2 linear [Ag(NH3)2]+ 3 trigonal planar [Cu(CN)3]2− 4 tetrahedral(d0 or d10), low oxidation...

Predicting Molecular Geometry

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2020

VSEPR Theory for Determination of Electron Pair Geometries The following procedure uses VSEPR theory to determine the electron pair geometries and the molecular structures: Write the Lewis structure of the molecule or polyatomic ion. Count the number of electron groups (lone pairs and bonds) around the central atom. A single, double, or triple bond counts as one region of electron density. Identify the electron-pair geometry based on the number of electron groups: linear, trigonal planar,...

Research

JoVE EoE - Neuroimaging

Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging to Visualize Multiple Sclerosis Lesions

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2025

Position the head of a patient with multiple sclerosis inside the radiofrequency or RF coil of an MRI machine.Begin fluid-attenuated inversion recovery or FLAIR imaging. Select a brain slice containing lesions near CSF-rich areas.The system generates a strong magnetic field, aligning protons in healthy and lesioned brain tissue and CSF along its direction, creating net magnetization.Apply an inversion RF pulse to flip the magnetization of all protons, aligning them opposite to the magnetic...

Geometry of Hyperbolas

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2025

A hyperbola consists of all points where the absolute difference of distances to two fixed points, called foci, remains constant. The standard equation isEach branch extends infinitely and approaches two asymptotes, which guide the curve’s behavior. The parameters a and b define key features: a measures the distance from the center to each vertex along the transverse axis, while b influences the slopes of the asymptotes. The asymptotes have equationsA rectangle centered at the origin with...

Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging

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Cited by 7 •

2015

The bioorthogonal inverse electron demand Diels-Alder cycloaddition has been harnessed to create an effective and modular pretargeted PET imaging strategy for cancer. In this protocol, the steps of this methodology are described in the context of a model system employing the colorectal cancer targeted antibody huA33 and a 64Cu-labeled radioligand.

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