Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

Alice Sosic; Marta Cappellini; Matteo Scalabrin; Barbara Gatto

doi:10.3791/52474

ジャーナル

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免疫学と感染

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ヌクレオカプシドアニーリング媒介電気泳動（NAME）アッセイは、HIV-1ヌクレオカプシド阻害剤の迅速な同定を可能にする

JoVE Journal
免疫学と感染

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JoVE Journal 免疫学と感染

Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors

ヌクレオカプシドアニーリング媒介電気泳動（NAME）アッセイは、HIV-1ヌクレオカプシド阻害剤の迅速な同定を可能にする

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8,839 Views

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08:33 min

•

January 19, 2015

DOI:

10.3791/52474-v

DOI:

10.3791/52474-v

•

08:33 min

January 19, 2015

•

7 Views

Alice Sosic¹, Marta Cappellini¹, Matteo Scalabrin², Barbara Gatto¹

¹Department of Pharmaceutical and Pharmacological Sciences,University of Padova, ²The RNA Institute,SUNY Albany

概要

This protocol describes NAME, an assay that allows the rapid identification of molecules able to inhibit in vitro the chaperone activities of HIV-1 nucleocapsid protein.

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ヌクレオカプシドアニーリング媒介電気泳動（NAME）アッセイは、HIV-1ヌクレオカプシド阻害剤の迅速な同定を可能にする

概要

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