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Medicine
複雑な腹腔鏡下胆嚢摘出術ナビゲーションにおけるインドシアニン緑色蛍光の役割
複雑な腹腔鏡下胆嚢摘出術ナビゲーションにおけるインドシアニン緑色蛍光の役割
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JoVE Journal Medicine
The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

複雑な腹腔鏡下胆嚢摘出術ナビゲーションにおけるインドシアニン緑色蛍光の役割

Full Text
1,464 Views
03:27 min
January 31, 2025

DOI: 10.3791/67562-v

Luyao Zhang*1, Xialei Liu*1, Baojia Zou*1, Jian Li1, Chaonong Cai, Peiping Li1

1Department of Hepatobiliary Surgery and Liver Transplantation,The Fifth Affiliated Hospital of Sun Yat-sen University

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Please note that some of the translations on this page are AI generated. Click here for the English version.

Overview

This protocol outlines the steps for fluorescence-guided laparoscopic cholecystectomy and elucidates the role of fluorescence navigation in diverse surgical scenarios. The study focuses on optimizing the timing and dosage of indocyanine green for improved visualization of bile ducts during surgery.

Key Study Components

Area of Science

  • Fluorescence imaging
  • Laparoscopic surgery
  • Surgical navigation

Background

  • Complex laparoscopic cholecystectomy presents challenges in bile duct visualization.
  • Indocyanine green is a dye used for enhancing imaging during surgery.
  • Fluorescence imaging technology has advanced to improve surgical outcomes.
  • Optimal timing and dosage of dye administration are critical for effectiveness.

Purpose of Study

  • To determine the optimal timing for indocyanine green injection.
  • To assess the dosage required for effective bile duct visualization.
  • To enhance intraoperative navigation and reduce surgical complications.

Methods Used

  • Administer 0.25 mg of indocyanine green via peripheral vein injection 45 minutes before surgery.
  • Utilize the DPMI fluorescence system for imaging.
  • Operate the system in both white light and near-infrared spectrums.
  • Evaluate the effectiveness of fluorescence imaging in real-time during surgery.

Main Results

  • Indocyanine green significantly improves visualization of bile ducts.
  • Optimal timing and dosage enhance surgical navigation.
  • Fluorescence imaging aids in reducing intraoperative complications.
  • Results support the use of fluorescence-guided techniques in complex surgeries.

Conclusions

  • Fluorescence-guided laparoscopic cholecystectomy is a valuable technique.
  • Indocyanine green is effective for enhancing bile duct visualization.
  • Further studies may optimize protocols for broader surgical applications.

Frequently Asked Questions

What is fluorescence-guided laparoscopic cholecystectomy?
It is a surgical technique that uses fluorescence imaging to improve visualization of bile ducts during laparoscopic cholecystectomy.
How is indocyanine green administered?
Indocyanine green is administered via peripheral vein injection 45 minutes before the surgery.
What are the benefits of using fluorescence imaging?
Fluorescence imaging enhances visualization, aids in navigation, and can reduce surgical complications.
What is the role of the DPMI fluorescence system?
The DPMI system is a dual-channel device that operates in white light and near-infrared spectrums for imaging during surgery.
What are the main findings of the study?
The study found that indocyanine green significantly improves bile duct visualization and enhances surgical outcomes.
Can fluorescence-guided techniques be used in other surgeries?
Yes, the findings may support the use of fluorescence-guided techniques in various surgical applications.

このプロトコルは、蛍光ガイド下腹腔鏡下胆嚢摘出術の手順を概説し、さまざまな手術シナリオにおける蛍光ナビゲーションの役割を解明します。

私たちの研究は、これらの複雑な腹腔鏡下胆嚢摘出術における蛍光イメージングの応用に関するものです。私たちの研究の主な目的は、術前のインドシアニングリーン注射の最適なタイミングと投与量を見つけることです。複雑な腹腔鏡下胆嚢摘出術における最新の開発は、現在取り組んでいる蛍光イメージングなど、胆管のより良い視覚化に関するものです。

私たちの研究は、これらの複雑な腹腔鏡下胆嚢摘出術におけるインドシアニングリーンの価値を確認しており、胆管のより良い術中視覚化に役立ちます。まず、手術の45分前に末梢静脈注射で0.25ミリグラムのインドシアニングリーンを患者に投与します。デュアルチャネルの画像誘導デバイスであるDPMI蛍光システムをセットアップして、白色光と近赤外スペクトルで動作します。

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