異種移植における急性細胞拒絶反応および抗体介質拒絶反応の研究を用いる3人による標準化マウスモデル
293 回視聴
•
08:42 分
•
2026年3月20日
DOI :10.3791/68756-v
2026年3月20日
•293 回視聴
Xiaofei Zhu1,2 , Jian Huang2,3 , Yuqi An3,4 , Peiyuan Li2,3,5 , Kai Xing2,3,5 , Yuan Chang2,3,5 , Jiangping Song2,3,5,6,7,8
1Department of Urology, Beijing Jishuitan Hospital Affiliated to Capital Medical University, 2Beijing Key Laboratory of Organ Xenotransplantation, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 3State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 4First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, 5Department of Cardiac Surgery, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 6Department of Cardiac Surgery, Fuwai Yunnan Hospital, Chinese Academy of Medical Sciences, Affiliated Cardiovascular Hospital of Kunming Medical University, 7Shenzhen Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, 8Sanya Institute of China Agricultural University
本研究は、急性細胞拒絶反応および急性抗体介在拒絶反応を特異的に再現するために、2つの標準化されたマウス異種移植モデルを確立します。これらのモデルは、異種移植片の免疫拒絶反応のメカニズムの調査、免疫抑制戦略の評価、前臨床異種移植研究の進展に信頼できるプラットフォームとして機能します。
Chapters in this video
0:00
Introduction
0:50
Donor Heart Harvest
3:01
Recipient Vessel Preparation
5:12
Cervical Heterotopic Heart Transplantation
6:34
Results
8:06
Conclusion
Related Videos
著作権 © 2026 MyJoVE Corporation. 無断転載を禁じます。