Name: homeostasis and negative feedback
Uploaded: 2023-06-23T15:38:43.000Z
Duration: 1 min 16 s
Channel: JoVE

K12 Standards

north-carolina-k-12-science-standard-course-of-study

North Carolina K-12 Science Standard Course of Study

9-12

Biology

from-molecules-to-organisms-structures-and-processes

From Molecules to Organisms- Structures and Processes

LS.Bio.3.1

What is Homeostasis?

항상성은 변화하는 외부 환경에 대응하여 안정적인 내부 상태를 유지하는 신체의 능력입니다.
예를 들어, 바깥 날씨가 따뜻할 때 사람의 체온이 상승하기 시작할 수 있으며, 신체는 상승에 대응하기 위해 반응해야 합니다.
수용체(Receptor), 제어 센터(control center) 및 효과기(effector)는 변수에 반응하는 데 필요한 생리적 변화를 조정합니다.
체온이 상승하는 경우, 피부 세포의 열 수용체는 상승된 온도를 감지하고 신경 자극을 통해 그 메시지를 제어 센터인 뇌에 전달합니다.
뇌는 자극을 설정점(변수의 생리적 범위)과 비교합니다. 정상적인 인체 온도의 설정값은 약 37°C입니다.
체온이 설정점을 초과하면 뇌는 땀을 생성하도록 효과기, 즉 땀샘에 신호를 보냅니다. 땀의 증발은 몸을 식힙니다.
체온이 설정값으로 돌아오면 수용체가 뇌에 피드백을 보내 땀 생성을 줄여 항상성을 유지합니다.

항상성이란?

항상성을 유지하려면 신체가 지속적으로 내부 상태를 유지해야 합니다. 각 생리적 상태에는 체온에서 혈압, 특정 영양소 수준에 이르기까지 특정 설정점이 있습니다. 설정점은 정상 범위가 변동하는 생리적 값입니다. 정상 범위는 최적의 건강하고 안정적인 제한된 값 집합입니다. 예를 들어, 정상적인 인체 온도의 설정점은 약 37℃(98.6℉)입니다. 체온과 혈압과 같은 생리적 매개변수는 정상 범위 내에서 그 지점보다 몇 도 위아래로 변동하는 경향이 있습니다. 뇌와 신체의 다른 부분에 있는 제어 센터는 항상성에서의 편차를 모니터링하고 부정적 피드백을 사용하여 반응합니다. 부정적 피드백은 설정점에서의 편차를 역전시키는 작용입니다. 따라서 부정적 피드백은 신체 매개변수를 정상 범위 내에서 유지합니다. 항상성 유지는 신체 전체에서 부정적 피드백으로 이루어지며, 부정적 피드백을 이해하는 것은 인간의 생리학을 이해하는 데 필수적입니다. 센서는 수용체라고도 하며, 생리적 값을 모니터링하는 피드백 시스템의 구성 요소입니다. 이 값은 제어 센터에 전달됩니다. 제어 센터는 값을 정상 범위와 비교하는 피드백 시스템의 구성 요소입니다. 값이 설정 지점에서 너무 많이 벗어나면 제어 센터가 효과기를 활성화합니다. 효과기는 상황을 역전시키고 값을 정상 범위로 되돌리는 변화를 일으키는 피드백 시스템의 구성 요소입니다. 예를 들어, 시스템을 작동시키려면 자극이 생리적 매개변수를 정상 범위(항상성 이상)를 넘어야 합니다. 이 자극은 특정 센서에 의해 '들립니다.' 혈당 조절에서 췌장의 특정 내분비 세포는 혈류에서 과도한 포도당(자극)을 감지합니다. 이 췌장 베타 세포는 혈당 수치가 증가하면 호르몬 인슐린을 혈류로 방출하여 대응합니다. 인슐린은 골격근 섬유, 지방 세포(지방세포), 간 세포에 신호를 보내 과도한 포도당을 흡수하여 혈류에서 제거합니다. 혈류의 포도당 농도가 떨어지면 농도 감소(실제 부정적 피드백)가 췌장 알파 세포에 의해 감지되고 인슐린 방출이 중단됩니다. 이렇게 하면 혈당 수치가 정상 범위 아래로 계속 떨어지는 것을 방지할 수 있습니다. 이 문서는 <a href="https://openstax.org/books/anatomy-and-physiology-2e/pages/">Openstax, Anatomy and Physiology 2e, Section 1.5: </a>Homeostasis 에서 발췌되었습니다.

항상성을 유지하려면 신체가 내부 조건을 지속적으로 유지해야 합니다. 각 생리적 상태에는 특정 설정점이 있습니다.

Education

교육

JoVE Core

Anatomy and Physiology

해부학 및 생리학

Unit 1

제1단원

Introduction to the Human Body

KEY TERMS AND CONCEPTS

주요 용어 및 개념

homeostasis and negative feedback

Homeostasis keeps the body’s internal conditions stable. The body does this by holding each physiological condition near a set point. A set point is the value around which the normal range changes, and the normal range is the small group of values that is healthiest and most stable. Human body temperature is a common example. Its set point is about 37°C, or 98.6°F, and it can shift a little above or below that point while still staying in range.

Negative feedback helps maintain homeostasis. This process reverses a change that moves a body value away from its set point. Control centers in the brain and other body parts monitor these changes and respond when conditions drift too far. Because this happens throughout the body all the time, negative feedback is a key idea in human physiology.

A feedback system has three main parts: a sensor, a control center, and an effector. A sensor, also called a receptor, watches a physiological value and sends that information to the control center. The control center compares the value with the normal range. If the value moves too far from the set point, the control center activates an effector. The effector causes a change that brings the value back toward normal.

Blood glucose control shows how this works. When blood sugar rises too high, pancreatic beta cells detect the excess glucose in the bloodstream. These endocrine cells release insulin into the blood. Insulin tells skeletal muscle fibers, fat cells, and liver cells to take up the extra glucose, which removes it from the bloodstream. As glucose levels fall, pancreatic alpha cells detect the drop, and insulin release stops. This keeps blood sugar from falling below the normal range.

Homeostasis and Negative Feedback

overview of anatomy and physiology

How Anatomy and Physiology Work Together

Human anatomy studies the structures of the body. Some body structures are so small that they can only be seen and examined with a microscope. Others are large enough to be viewed, handled, measured, and weighed. The word anatomy comes from a Greek root meaning “to cut apart.” Early study of the human body began with observing the outside of the body and the injuries seen in soldiers and other patients. Later, physicians were allowed to dissect dead bodies to learn more. Dissection means...

structural organization of the human body: an overview

structural-organization-of-the-human-body-an-overview

Levels of Organization in the Human Body

The human body is organized in levels that build from simple parts to a complete living being. These levels increase in complexity from subatomic particles, atoms, and molecules to organelles, cells, tissues, organs, organ systems, and the organism. At the chemical level, scientists study the smallest building blocks of matter. Matter is made of elements, which are pure substances such as hydrogen, oxygen, carbon, nitrogen, calcium, and iron. The smallest unit of an element is an atom, and...

functions of life

How the Human Body Keeps Going

Human life depends on metabolism, movement, development, growth, and reproduction. These functions help the body stay alive, maintain itself, and continue the species. Together, they show how the body uses energy and changes over time. Metabolism is the body’s use of energy and food molecules. It helps the body make fuel for movement, support body functions, and build and maintain body structures. Metabolism includes two kinds of reactions: anabolism and catabolism. Anabolism is the process...

requirements for human life

Human Survival Needs in the Body

Human survival depends on air, water, food, a narrow temperature range, and a narrow range of atmospheric pressure. The Earth and its atmosphere provide these conditions, but the body can only function well when they stay within limits. Oxygen is one of the most important needs. Atmospheric air is only about 20 percent oxygen, but that oxygen supports the chemical reactions that keep the body alive, including the reactions that make ATP. Brain cells are especially sensitive to a lack of oxygen...

what is homeostasis?

Homeostasis keeps the body’s internal conditions stable. The body does this by holding each physiological condition near a set point. A set point is the value around which the normal range changes, and the normal range is the small group of values that is healthiest and most stable. Human body temperature is a common example. Its set point is about 37°C, or 98.6°F, and it can shift a little above or below that point while still staying in range. Negative feedback helps maintain homeostasis.

negative and positive feedback

Feedback Loops in Body Balance

Negative and positive feedback help keep body conditions stable. These feedback loops control many body processes and support homeostasis, which is the maintenance of a steady internal environment. Negative feedback reduces a change and brings a system back toward its normal state. Positive feedback increases a change and pushes a process further in the same direction. Together, they show how the body can fine-tune responses when conditions shift. These control systems are important in many...

homeostatic imbalance

How Feedback Failure Disrupts Homeostasis

Homeostasis keeps the body’s internal conditions stable so cells, tissues, organs, and organ systems can work properly. The body uses control systems to regulate temperature, blood pressure, pH balance, and fluid balance. These controls depend on feedback loops, which can be positive or negative. Homeostatic imbalance happens when those feedback loops fail and the body can no longer maintain a stable internal environment. Injury, disease, environmental changes, genetic mutations, and aging can...

anatomical terminology

Anatomical Terms and Body Position

Anatomical terms help describe the human body clearly in biology and medicine. Health care professionals and anatomists use this standard language to avoid confusion and to make descriptions more precise. Most anatomical words come from Greek and Latin roots, and these roots usually stay the same because the languages are rarely used in everyday conversation. Many anatomical words are built from a root plus a prefix or suffix. The root often names an organ, tissue, or condition. The prefix or...

anatomical positions

Body Positions Used in Anatomy

Body positions used in anatomy give a shared way to describe where body parts are and how they face. These standard references help people talk about anatomical structures with the same meaning. The anatomical position is the main reference point for body orientation. In anatomical position, the body stands upright and faces forward. The feet are parallel and flat on the floor. The arms rest at the sides with the palms facing forward, and the head and eyes point forward. The most common...

regional terms

Anatomy Regions and Body Landmark Terms

Anatomy regions and body landmark terms help identify specific parts of the human body. These regional terms divide the body into areas with structures that support similar functions. They also make it easier to describe the exact area affected by an injury or disease. The human body is organized into two major regions: the axial region and the appendicular region. The axial region includes the body from the head to the abdomen and forms the central body axis. The appendicular region includes...

directional terms

Anatomical Direction and Body Position

Anatomical direction and body position terms help describe where one body structure is located in relation to another. These terms use comparisons, such as one tissue being inferior to another or a tumor being superficial to a deeper structure. They are based on the standard anatomical reference position, which uses the body in an upright pose. Anterior and posterior are a common pair of directional terms. Anterior, also called ventral, means toward the front of the body. Posterior, also...

body planes

Anatomy Sections and Body Planes

Anatomy sections and body planes are imaginary flat surfaces used to divide the body for study. They help show the orientation, relationships, and spatial layout of anatomical structures. These reference planes are also useful for describing organs and body parts in a standard way. The sagittal plane divides the body or an organ vertically into right and left sides. When that cut goes through the middle and makes equal halves, it is called the midsagittal or median plane. When it makes unequal...

anatomical movements

Body Joint Motion Terms

Body joint motion terms describe how bones and muscles move at different joints. These standard names make it easier to talk about range of motion in the body. They are used to describe actions at the shoulder, hip, elbow, knee, wrist, fingers, toes, and spine. Flexion and extension are movements in the sagittal plane, also called the anterior-posterior plane. Flexion is the forward bending motion of the head or vertebral column. Extension is the backward movement or straightening of a joint,...

abdominal regions and quadrants

Abdominal Pain and Organ Location

The abdominal cavity is divided into quadrants and regions to help locate organs and describe pain clearly. Clinicians and anatomists use imaginary lines to mark the abdominopelvic cavity. This system makes it easier to communicate about a patient’s symptoms or a suspicious mass. The simpler method divides the area into four quadrants. One horizontal line and one vertical line cross at the umbilicus, or navel. These quadrants are the right upper quadrant, right lower quadrant, left upper...

key terms and concepts

Learn how homeostasis stays stable through negative feedback, set points, sensors, control centers, and the insulin response to blood glucose.

Homeostasis and Negative Feedback | JoVE K12

anatomy and physiology

JoVE Core Anatomy and Physiology showcases the anatomical and physiological details of the human body in comprehensive, clear, and engaging video animations. This collection of lessons focuses on the structures, components, functions, and requirements of the human body. It is complemented by scientist-in-action videos that demonstrate the application of this knowledge in real-world medical and research settings.

Pennsylvania State Academic Standards

Life Science

Structure and Function

3.1.9-12.C

Louisiana Student Standards for Science

High School

Life Sciences

From Molecules To Organisms: Structures And Processes

HS-LS1-3

ohios-learning-standards-and-model-curriculum

Ohio’s Learning Standards and Model Curriculum

Cells

Cell structure and function

Human Anatomy and Physiology

Levels Of Organization

Homeostasis

Virginia  Standards of Learning

HIgh School

BIO.2

BIO.2.a

Minnesota Academic Standards in Science

1.2.1 9L.1.2.1.1

new-jersey-student-learning-standards-for-science

New Jersey Student Learning Standards for Science

From Molecules to Organisms: Structures and Processes

Arizona Science Standards

HS.L1

HS.L1U1.20

Alabama Course of Study Science

9-12.B.1.4

Next Generation Science Standards

Texas Essential Knowledge and Skills

BIO.5

BIO.5.C

BIO.12

BIO.12.A

south-carolina-college-and-career-ready-science-standards

South Carolina College and Career Ready Science Standards

B-LS1-3.

new-york-state-science-learning-standards

New York State Science Learning Standards

HS-LS1-3.

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Homeostasis and Negative Feedback

Description

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