Bone Porosity

Bone porosity is the proportion and organization of void spaces within bone tissue, a structural feature that influences both mechanical performance and biological function. These pores form through the activity of bone-resorbing and bone-forming cells, and their size, connectivity, and distribution regulate fluid transport, nutrient exchange, and resistance to fracture. In bioengineering, measuring and modeling bone porosity helps researchers assess osteoporosis and other skeletal disorders, design biomimetic scaffolds, and optimize implant integration. Porosity analysis using imaging and computational methods also supports the development of lightweight materials that reproduce bone’s balance of strength, permeability, and regenerative capacity.

Bone Porosity - Related Videos

Education

JoVE Core - Civil Engineering

Porosity and Absorption of Aggregate

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2024

Aggregates contain pores of varying sizes; while some are completely enclosed within the particles, others open onto the surface, allowing water to penetrate. The porosity of aggregates is a major factor contributing to the overall porosity of concrete, given that aggregates constitute about three-quarters of concrete's volume. When all pores in an aggregate are filled with water, the aggregate is considered saturated and surface-dry. If left in dry air, water will evaporate until the aggregate...

Porosity in Cement Paste

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2024

The porosity of concrete is a measure of the void spaces within its structure. These spaces impact its strength and durability significantly. When water and cement interact, a chemical reaction called hydration creates a semi-solid paste. This paste includes combined water, making up approximately 23% of the cement's dry mass, and gel water, which fills minuscule voids known as gel pores, accounting for about 28% of the cement gel volume. The balance of water to cement in the mix is critical—it...

Research

JoVE Journal - Chemistry

Archimedes-Based Glycerol Displacement for Electrode Porosity Measurement in Lead-Acid Batteries

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2026

Here, we present a simple and low-cost glycerol displacement method based on Archimedes' principle for measuring lead-acid battery electrode porosities. The method demonstrates good reproducibility and is safer than traditional techniques, requiring low-hazard chemicals and equipment. Combining the technique with microstructural analysis by X-ray diffraction provides information on battery electrode properties and degradation.

Microbubble Fabrication of Concave-porosity PDMS Beads

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Cited by 2 •

2015

Procedures used to generate microstructured concave-porosity polydimethylsiloxane beads are presented. Effects of electrolyte concentration and identity within the aqueous phase are particularly emphasized.

Models of Bone Metastasis

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Cited by 115 •

2012

Animal models are frequently utilized to study cancer metastasis to bone. In this protocol we will describe two common methods of tumor inoculation for bone metastasis studies and briefly describe some of the analyses utilized to monitor and quantify these models.

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