Buccal Osteotomy
Buccal Osteotomy - Related Videos
05:09
Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
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Cited by 3 •
2023
In the present protocol, a urethral stricture induction was developed in Wistar rats, followed by urethral reconstruction with a buccal mucosa graft. A retrograde urethrogram and laser Doppler assessment were performed, validating urethral reconstruction (after stricture formation) and graft placement.
07:41
An Intramedullary Locking Nail for Standardized Fixation of Femur Osteotomies to Analyze Normal and Defective Bone Healing in Mice
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Cited by 10 •
2016
This protocol describes an osteosynthesis technique using an intramedullary locking nail for standardized fixation of femur osteotomies, which can be used to analyze normal and defective bone healing in mice.
10:09
Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
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Cited by 19 •
2014
One constraint of preclinical research in the field of bone repair is the lack of experimental control over the local mechanical environment within a healing bone lesion. We report the design and use of an external fixator for bone repair with the ability to change fixator stiffness in vivo.
05:43
Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
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2022
Here, we present a protocol to iatrogenically fracture the shaft of the femur of Wistar albino rats and follow up on the development of the callus. This femur osteotomy model can help researchers evaluate the process of fracture healing and to study how a drug could influence fracture healing.
05:45
Stabilizing a Femur Osteotomy with a Plate Fixation in Ambystoma mexicanum
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2024
A protocol for femoral osteotomy surgery with the use of internal plate fixation in mature axolotls is presented. The procedure can be used to perform comparative studies on limb regeneration and fracture healing in aquatic amphibians.
FAQs
After the controlled osseous defect is created, healing progresses through inflammation, new bone formation, and remodeling. These stages provide a biological timeline for judging whether an engineered intervention supports repair rather than merely filling the initial space. Tracking this sequence helps researchers relate defect closure and tissue integration to the progression of jawbone healing.
A standardized defect makes results more comparable across experimental treatments. Preserving defined surrounding structures and controlling the osseous defect limits unintended variation, allowing researchers to attribute differences more confidently to a biomaterial, scaffold, implant, or biologically active treatment. This reproducibility strengthens comparisons of how different strategies influence jawbone repair.
Three central outcomes are defect closure, tissue integration, and mechanical stability. Defect closure indicates how much of the created space has been repaired, while tissue integration shows how the repaired region connects with surrounding structures. Mechanical stability adds information about functional support, helping researchers evaluate engineered therapies from complementary structural and biological perspectives.
The workflow includes creating a controlled osseous defect with an osteotomy instrument, sectioning the buccal cortical plate, and preserving defined surrounding structures. After the intervention or test treatment is applied, the defect is allowed to heal through its biological repair sequence. This arrangement provides a consistent basis for evaluating regeneration and integration.
The model can be used to assess biomaterials, scaffolds, implants, and biologically active treatments intended to support bone regeneration. Researchers examine how these approaches affect repair within a controlled jawbone defect, then use outcomes such as closure, integration, and stability to compare their performance and potential value for oral and maxillofacial interventions.
It links controlled bone injury with measurable healing outcomes, giving bioengineers a structured way to test repair strategies before translating findings into oral and maxillofacial applications. Evidence from defect closure, tissue integration, and mechanical stability can guide refinement of engineered therapies and clarify how well they support the restoration of jawbone structure.