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Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
JoVE Journal
Medicine
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JoVE Journal Medicine
Protocol for Developing a Femur Osteotomy Model in Wistar Albino Rats
DOI:

05:43 min

August 31, 2022

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Chapters

  • 00:04Introduction
  • 01:18Surgical Procedure for Creating Complete Transverse Fracture Through Open Osteotomy
  • 03:38Results: X-Ray of the Femur, Bone with Callus Obtained After Optimal Decalcification, and H&E Staining of the Fracture Site
  • 04:52Conclusion

Summary

Automatic Translation

Here, we present a protocol to iatrogenically fracture the shaft of the femur of Wistar albino rats and follow up on the development of the callus. This femur osteotomy model can help researchers evaluate the process of fracture healing and to study how a drug could influence fracture healing.

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