Three-dimensional Devices
Three-dimensional Devices - Related Videos
11:33
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
0 Views •
Cited by 12 •
2017
We detail a method to fabricate three-dimensional paper-based microfluidic devices for use in the development of immunoassays. Our approach to device assembly is a type of multilayer, additive manufacturing. We demonstrate a sandwich immunoassay to provide representative results for these types of paper-based devices.
05:40
Generation of Three-Dimensional Spheroids/Organoids from Two-Dimensional Cell Cultures Using a Novel Stamp Device
0 Views •
Cited by 2 •
2025
This study presents a cost-effective and efficient methodology for generating 3D cell structures using a stamp-based system to create microwells in agarose molds. The system promotes the formation of uniform spheroids/organoids, thus improving cell interactions. This approach reduces experimental variability and supports applications in drug testing and tissue engineering.
08:29
Thermal Measurement Techniques in Analytical Microfluidic Devices
0 Views •
Cited by 6 •
2015
Here, we present three protocols for thermal measurements in microfluidic devices.
05:17
Three-Dimensional Acoustic Assembly Device for Mass Manufacturing of Cell Spheroids
0 Views •
2023
Cell spheroids have been considered one potential model in the field of biological applications. This article describes protocols for scalably generating cell spheroids using a 3D acoustic assembly device, which provides an efficient method for the robust and rapid fabrication of uniform cell spheroids.
08:28
Overview of BioMEM Devices
0 Views •
2023
Bio-microelectromechanical systems, also called BioMEMs, are microscale devices that enable the use of small sample and reagent volumes for diagnostic devices in vivo and in vitro. These devices perform various functions such as filtration, sensing, or synthesis on the microscale, enabling cost savings and improved sensitivity. This video introduces BioMEMs, touches on their use in the bioengineering field, and presents some prominent methods used in fabrication. Additionally, this video...
FAQs
Performance depends on how materials, channels, sensors, and biological components are positioned through the device volume. Their arrangement governs transport, mechanical behavior, and interactions at different locations, so changing the internal architecture can alter how the system functions. This makes spatial design a central consideration when developing bioengineering platforms for controlled biological environments.
A planar device primarily organizes functional elements across a surface, whereas a three-dimensional design distributes them through height, width, and depth. That added spatial dimension enables functions based on volume-wide organization and interactions. In bioengineering, this distinction supports systems that more closely reproduce the organization and physical conditions found in biological settings.
Materials, channels, sensors, and biological components each contribute to device behavior, but their placement is equally important. Together, these features determine how substances move, how the structure responds mechanically, and how components interact throughout the volume. Adjusting their arrangement can therefore influence both the operating performance and the biological relevance of the engineered system.
The main distinction is the extent to which functional organization occupies the device volume. Three-dimensional devices can represent biological structure and physical conditions across depth, while planar platforms provide less spatial dimensionality. This difference is relevant when researchers need models or devices that better reflect tissue organization, cellular environments, or other volume-dependent features.
Development requires coordinating the spatial arrangement of functional elements with fabrication and integration methods. The resulting structure must support the intended transport, mechanical behavior, and interactions throughout its volume. Advances in these processes may improve control over cellular environments and overall device performance, making fabrication strategy an important part of bioengineering development.
In tissue engineering and cell culture, these systems can provide environments that more closely reproduce biological organization and physical conditions. Their internal arrangement helps control the surroundings experienced by cells and tissues. Such control may support the development of more representative laboratory models and improve the ability to study or engineer biological behavior.
Three-dimensional devices support diagnostic platforms and medical-device development by integrating functional structures across a device volume. Their spatial organization can influence transport, mechanical behavior, and component interactions, which are important for performance. These systems may therefore help connect engineered design with biomedical requirements during development and evaluation.
Three-dimensional devices can bridge laboratory studies and biomedical applications by combining controlled cellular environments with engineered device performance. Their organization more closely reflects biological systems than a purely planar arrangement, while fabrication and integration advances can improve control and reproducibility. This combination may strengthen the relevance of laboratory models for future biomedical translation.