Non-cavitated Lesions
Non-cavitated Lesions - Related Videos
14:22
Activating Molecules, Ions, and Solid Particles with Acoustic Cavitation
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Cited by 6 •
2014
Acoustic cavitation in liquids submitted to power ultrasound creates transient extreme conditions inside the collapsing bubbles, which are the origin of unusual chemical reactivity and light emission, known as sonoluminescence. In the presence of noble gases, nonequilibrium plasma is formed. The "hot" particles and the photons generated by collapsing bubbles are able to excite species in solution.
08:24
Nitrogen Cavitation and Differential Centrifugation Allows for Monitoring the Distribution of Peripheral Membrane Proteins in Cultured Cells
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Cited by 15 •
2017
Here we present protocols for detergent-free homogenization of cultured mammalian cells based on nitrogen cavitation and subsequent separation of cytosolic and membrane-bound proteins by ultracentrifugation. This method is ideal for monitoring the partitioning of peripheral membrane proteins between soluble and membrane fractions.
11:14
A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)–Cell Interaction and the Resultant Bioeffects at the Single-cell Level
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Cited by 8 •
2017
A microfluidic chip was fabricated to produce pairs of gold dots for tandem bubble generation and fibronectin-coated islands for single-cell patterning nearby. The resultant flow field was characterized by particle image velocimetry and was employed to study various bioeffects, including cell membrane poration, membrane deformation, and intracellular calcium response.
07:36
Studying Cavitation Enhanced Therapy
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Cited by 6 •
2021
The presented experimental protocol can be used to perform real time measurements of cavitation activity in a cell culture device with the aim of enabling investigation of the conditions required for successful drug delivery and/or other bioeffects.
09:22
Sectioning Mammary Gland Whole Mounts for Lesion Identification
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Cited by 13 •
2017
We developed a method to successfully remove, process, section, and stain, for histopathological evaluation, mammary tissue that had originally been fixed on slides as whole mounts. This method may promote the collection and evaluation of mammary gland whole mounts in reproductive and developmental test guideline studies.
FAQs
Bacterial acids in dental biofilm repeatedly lower the local pH, creating conditions that favor mineral leaving enamel or dentin. When these acidic episodes recur, the balance shifts toward demineralization, even though the outer tooth surface has not yet collapsed. This pH-driven process explains why early lesions can progress before an obvious structural defect appears.
The visible color change reflects mineral loss within the tooth tissues rather than an open hole. A chalky white opacity may signal an early alteration, while brown opacity can also occur as the lesion develops. These appearances give clinicians visual clues that support identification of mineral change before structural collapse becomes evident.
An intact surface maintains the physical structure of the tooth while mineral loss occurs beneath or within it. This condition creates an opportunity to manage the lesion without immediately removing tooth structure. Preventive measures, including fluoride exposure and improved plaque control, can promote remineralization and support a minimally invasive approach.
Identification can begin with visual examination, using changes such as chalky white or brown opacity as clinical clues. Adjunctive detection methods may provide additional information when visual findings alone are insufficient. Recognizing these lesions at the early stage helps distinguish preserved-surface disease from later caries with structural breakdown.
Management centers on reducing conditions that favor ongoing mineral loss and encouraging remineralization. Improved plaque control addresses the bacterial biofilm associated with repeated acid production, while fluoride exposure supports mineral recovery. Because the surface remains intact, this preventive strategy can avoid immediate structural intervention and preserve more of the natural tooth.
These lesions provide a model for observing how bacterial biofilm, acidity, mineral loss, and surface preservation interact during caries progression. Their study connects biological mechanisms with clinical decision-making: detecting change early allows preventive management before structural collapse. This relationship supports minimally invasive dentistry by emphasizing preservation of intact tooth tissue whenever possible.