Submandibular Vein Bleed

Submandibular vein bleed is a biological sampling procedure that collects blood from the veins beneath the lower jaw, providing a way to obtain specimens for laboratory analysis. A controlled puncture breaches the venous wall, allowing blood to exit; applying pressure afterward promotes hemostasis and limits blood loss. In biology and biomedical research, this method can support hematology, serum chemistry, and immune studies when repeated or minimally invasive blood collection is needed. Accurate anatomical targeting and careful handling help preserve sample quality while reducing tissue injury and animal stress.

Submandibular Vein Bleed - Related Videos

Research

JoVE EoE - Rodent Models

Murine Model of Islet Transplantation: A Surgical Method to Infuse Pancreatic Islets in Portal Vein and Prevention of Postoperative Bleeding

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2025

In this video, we describe a procedure to infuse pancreatic islet cells into the hepatic portal vein, followed by application of gel foam to successfully prevent bleeding. Postoperative bleeding is a common cause of high mortality during islet transplantation.

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice

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Cited by 6 •

2021

The refined tail vein transection (TVT) bleeding model in anesthetized mice is a sensitive in vivo method for the assessment of hemophilic bleeding. This optimized TVT bleeding model uses blood loss and bleeding time as endpoints, refining other models and avoiding death as an endpoint.

Minimizing Post-Infusion Portal Vein Bleeding during Intrahepatic Islet Transplantation in Mice

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Cited by 1 •

2021

Here we present refined surgical procedures on successfully performing intraportal islet transplantation, a clinically relevant but technically challenging surgical procedure, in mice.

Cannulation of the Mouse Submandibular Salivary Gland via the Wharton's Duct

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Cited by 17 •

2011

A protocol for the cannulation of the mouse submandibular salivary gland via the Wharton's duct is described. For this experiment, the trypan blue solution is used as a dyer to demonstrate how this technique effectively delivers infusions into the targeted gland, and to suggest the reliability of this new approach as a potential clinical drug/cell therapy for the regeneration of salivary glands.

Education

JoVE Core - Civil Engineering

Bleeding in Fresh Concrete

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2024

Bleeding in fresh concrete occurs when water from the mix rises to the surface. This happens because the mix's solid components fail to retain all the water as they settle, leading to separation where water collects at the top. The severity of bleeding can be measured by assessing the total settlement or by noting the decrease in height per unit height of concrete. Bleeding can cause several issues in the concrete structure. Sometimes, the rising water gets trapped beneath large aggregate...

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