Valvular Stenosis

Valvular stenosis is a condition in which a heart valve becomes narrowed, restricting forward blood flow and increasing the workload on the heart. The reduced opening creates resistance to ejection, producing a pressure gradient across the valve and potentially causing chamber thickening, reduced cardiac output, or congestion as disease progresses. In clinical practice, evaluation combines symptoms, physical examination, and cardiac imaging, especially echocardiography, to assess valve structure, blood-flow velocity, and severity. These findings guide monitoring and treatment, which may include medication for associated symptoms or procedures such as balloon valvuloplasty, valve repair, or valve replacement.

Valvular Stenosis - Related Videos

Research

JoVE Journal - Biology

Isolation of Valvular Endothelial Cells

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Cited by 82 •

2010

We provide a method for isolating and culturing pure populations of heart valve endothelial cells (VEC). VEC can be isolated from either side of the cusp or leaflet and immediately following, underlying interstitial cell (VIC) isolation is straightforward.

Isolation and Culture of Avian Embryonic Valvular Progenitor Cells

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Cited by 4 •

2010

This article will provide a method for isolating and culturing quail or chicken HH14- valve endocardial cells and HH25 valve cushion mesenchymal cells.

Surgical Management of Meatal Stenosis with Meatoplasty

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Cited by 13 •

2010

Meatoplasty, surgical management of meatal stenosis.

Full-Endoscopic Interlaminar Approach for Decompression of Lateral Recess Stenosis

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Cited by 1 •

2023

Technical advances and increased experience in full-endoscopic spinal surgeries enable these procedures to be performed with minimal incision, muscle retraction, and bone removal.

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis

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2025

Pulmonary vein stenosis (PVS) is a life-threatening complication of fibrosing mediastinitis (FM), with a poor prognosis if not properly treated. Currently, catheter-based endovascular angioplasty is a promising therapeutic strategy for FM-associated PVS. This protocol primarily outlines a stepwise approach to the transcatheter procedure for FM-associated PVS.

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