Age-standardized Rates

Age-standardized rates are epidemiological measures that adjust disease, death, or other health-event rates to a common age distribution, enabling fair comparisons between populations with different age structures. The method applies age-specific rates from each population to a selected standard population, then combines the resulting expected numbers of events into a summary rate. In medicine, age-standardized rates help assess cancer incidence, mortality, disease burden, and healthcare outcomes across countries, regions, or time periods without allowing differences in population age to distort interpretation. They support surveillance, health policy, resource planning, and evaluation of prevention or treatment strategies.

Age-standardized Rates - Related Videos

Research

JoVE Journal - Engineering

Measurement of Outgassing Rates of Steels

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Cited by 5 •

2016

A protocol for the measurement of outgassing rates of hydrogen from ordinary steel vacuum chambers using the rate-of-pressure rise method is presented.

Continuous High-resolution Microscopic Observation of Replicative Aging in Budding Yeast

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Cited by 10 •

2013

We describe here the operation of a microfluidic device that allows continuous and high-resolution microscopic imaging of single budding yeast cells during their complete replicative and/or chronological lifespan.

Education

JoVE Science Education - Advanced Biology

An Introduction to Aging and Regeneration

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2023

Tissues are maintained through a balance of cellular aging and regeneration. Aging refers to the gradual loss of cellular function, and regeneration is the repair of damaged tissue generally mediated by preexisting adult or somatic stem cells. Scientists are interested in understanding the biological mechanisms behind these two complex processes. By doing so, researchers may be able to use somatic stem cells to treat degenerative diseases and develop therapies that could delay the effects of...

Research

JoVE Journal - Biology
Free Sample

Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate

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Cited by 103 •

2015

Glycolysis is a defining metabolic marker in multiple biological systems. Monitoring glycolysis by measuring the extracellular flux of H+ is common, but requires correction to be quantitative and unambiguous. Here, we demonstrate how to gather and correct extracellular flux data to distinguish between respiratory and glycolytic sources of extracellular acidification.

Frailty Assessment in an Aging Mouse Model

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2025

The goal of the present protocol is to provide instructions and guidelines for assessing physical frailty in C57Bl/6x129J laboratory mice. Specific details regarding each measure used in the physical frailty index are explained. Several methods for reporting frailty results are also presented.

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