Echocardiography Guided Delivery
Echocardiography Guided Delivery - Related Videos
06:47
Echocardiography-guided Injection for Targeted and Reliable Intramyocardial Stem Cell Delivery in a Rat Model of Myocardial Infarction
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2025
This article details an optimized protocol for echocardiography-guided intramyocardial injections in rat models of myocardial infarction using a 29 G x 88 mm needle. This technique ensures robust, precise, and reproducible delivery of therapeutic agents directly into the peri-infarct zone.
14:24
Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
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Cited by 2 •
2018
Novel therapeutic strategies in cardiac regenerative medicine require extensive and detailed studies in large preclinical animal models before they can be considered for use in humans. Here, we demonstrate a percutaneous contrast echocardiography-guided intramyocardial injection technique in rabbits, which is valuable for hypothesis testing the efficacy of such novel therapies.
08:04
Murine Fetal Echocardiography
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Cited by 7 •
2013
Fetal and perinatal death is a common feature when studying genetic alterations affecting cardiac development. High-frequency ultrasound imaging has improved 2-D resolution and can provide excellent information on early cardiac development and is an ideal method to detect the impact on cardiac structure and function prior to death.
08:09
Transthoracic Echocardiography in Mice
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Cited by 81 •
2010
Transthoracic echocardiography offers a noninvasive method for the evaluation of cardiac function in mice. A combination of ultrasound and Doppler imaging modalities can be used to obtain dimensional measurements of the heart and intracardiac blood flow, which together provide an assessment of cardiac systolic and diastolic performance.
09:00
Murine Echocardiography and Ultrasound Imaging
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Cited by 61 •
2010
This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
FAQs
Real-time ultrasound imaging shows cardiac anatomy while the catheter, device, or therapeutic material follows its intended pathway. Clinicians can therefore compare the delivery position with surrounding structures during the intervention rather than relying only on a final assessment. This continuous visual feedback supports more accurate alignment, placement, and deployment within the heart or nearby vessels.
Two-dimensional and three-dimensional echocardiography provide imaging views that help visualize anatomy and follow the delivery route. Using these views, clinicians can assess where a target lies in relation to cardiac structures and determine whether positioning is appropriate before deployment. The available imaging perspective supports procedural control when devices or therapeutic materials must reach a precise location.
Real-time monitoring allows clinicians to observe the target throughout positioning and deployment, then assess immediate effects within the heart or nearby vessels. This feedback can reveal whether the intervention has reached the intended location and whether the result appears appropriate at once. Such ongoing assessment helps reduce positioning errors and supports safer procedural decisions.
The procedure begins by using echocardiography to visualize relevant cardiac anatomy and establish the intended delivery pathway. Clinicians then guide a catheter, device, or therapeutic material toward the target while observing its movement with real-time two- or three-dimensional imaging. After positioning, they deploy the target and use the same imaging approach to assess immediate effects.
Its distinguishing feature is continuous, radiation-free visualization during the intervention. Instead of assessing placement only after a delivery step, clinicians can monitor anatomy, pathway, and target position as the procedure progresses. This may improve control over alignment and deployment while reducing positioning errors, making the approach useful for minimally invasive cardiovascular interventions.
Echocardiography-guided delivery supports minimally invasive cardiovascular interventions, including transcatheter procedures and targeted delivery of therapeutic materials. It is also relevant to emerging therapies that require accurate placement within the heart or nearby vessels. By combining procedural guidance with immediate assessment, the technique can help clinicians evaluate both delivery precision and the early effects of an intervention.