Metallic Interference Screws

Metallic interference screws are orthopedic fixation devices used to secure tendon or ligament grafts within bone tunnels, particularly during anterior cruciate ligament reconstruction. Their threaded design advances into the tunnel alongside the graft, creating radial compression and mechanical interference that stabilizes the graft against the surrounding bone while healing occurs. Typically manufactured from materials such as titanium or stainless steel, these screws provide immediate fixation and can support graft incorporation and restoration of joint stability. Their strength and radiographic visibility make them valuable in reconstructive surgery, although imaging artifacts and the potential need for later hardware removal remain important clinical considerations.

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Education

JoVE Core - Chemistry

Interference and Diffraction

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2020

Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other. Alternatively, if the two waves coincide and interact in a way such that the trough of one wave coincides with the peak of the other (in an out of phase manner), the resultant wave will...

Interference and Diffraction

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2023

Source: Yong P. Chen, PhD, Department of Physics & Astronomy, College of Science, Purdue University, West Lafayette, IN Interference and diffraction are characteristic phenomena of waves, ranging from water waves to electromagnetic waves such as light. Interference refers to the phenomenon of when two waves of the same kind overlap to give an alternating spatial variation of large and small wave amplitude. Diffraction refers to the phenomenon of when a wave passes through an aperture or...

RNA Interference

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2019

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated. This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...

Self-Locking Screw

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2023

A square-threaded screw jack is a mechanical device widely used for lifting heavy loads or applying considerable force. One of the key features that can make a screw jack more effective and reliable is its self-locking capability. A square-threaded screw jack carrying a load is considered self-locking if the screw retains its position even after the moment applied to it is removed. This occurs when the frictional force direction reverses, and the reaction force acts on the other side of the...

Research

JoVE Journal - Immunology and Infection
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RNA Interference in Ticks

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Cited by 51 •

2011

A method for RNA interference (RNAi) by injection of dsRNA into unfed ticks is described. RNAi is the most widely used gene-silencing technique in ticks where the use of other methods of genetic manipulation has been limited.

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