Negative Pressure Drainage

Negative pressure drainage is a medical technique that uses controlled suction to remove fluid, blood, or air from a wound or body cavity, supporting recovery and preventing accumulation. A sealed drainage system connects a catheter or porous dressing to a collection chamber, where pressure below that of the surrounding tissue draws material outward; regulated suction helps maintain flow while limiting tissue trauma. Clinicians use negative pressure drainage after surgery, for complex or infected wounds, and in conditions such as pneumothorax or fluid collections. By reducing edema, promoting wound approximation, and enabling fluid monitoring, the method can support healing and guide ongoing patient management.

Negative Pressure Drainage - Related Videos

Research

JoVE Journal - Biology
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Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression

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Cited by 7 •

2014

Cerebral perfusion is maintained across a range of pressures via cerebral autoregulation. However, characterizing autoregulation requires prominent pressure fluctuations at regulated frequencies. The described protocol will show how oscillatory lower body negative pressure can generate pressure fluctuations to provide data for projection pursuit regression for quantification of the autoregulatory curve.

Research

JoVE Journal - Medicine

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

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Cited by 31 •

2013

We describe a "gold standard" for evaluating orthostatic tolerance (OT) using tilt testing with combined lower body negative pressure (LBNP). This can be combined with non-invasive evaluations of cardiovascular reflex control. Normal and abnormal responses are defined.

Manual Drainage of the Zebrafish Embryonic Brain Ventricles

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Cited by 9 •

2012

We present a method to collect cerebrospinal fluid (CSF) and to create a system which lacks CSF within the embryonic zebrafish brain ventricular system. This allows for further examination of CSF composition and its requirement during embryonic brain development.

Synthesis and Microdiffraction at Extreme Pressures and Temperatures

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Cited by 5 •

2013

The laser heated diamond anvil cell combined with synchrotron micro-diffraction techniques allows researchers to explore the nature and properties of new phases of matter at extreme pressure and temperature (PT) conditions. Heterogeneous samples can be characterized in situ under high pressure by 2D mapping and combined powder, single-crystal and multigrain diffraction approaches.

Education

JoVE Core - Microbiology

Acid Mine Drainage

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2026

Mining activities that disturb sulfide-rich rocks, particularly those containing pyrite (FeS₂), initiate a cascade of geochemical and microbiological processes with serious environmental implications. When exposed to air and water, pyrite undergoes oxidation, releasing sulfate, ultimately forming sulfuric acid and mobilizing heavy metals into surrounding water systems. This phenomenon, known as acid mine drainage (AMD), results in low pH waters laden with toxic elements that threaten aquatic...

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